UPLC-Q-TOF/MS based fecal metabolomics reveals the potential anti-diabetic effect of Xiexin Decoction on T2DM rats

•Based on the fecal metabolomics, the underlying mechanism of Xiexin Decoction on the amelioration of T2DM by the metabolic activity of gut microbiota was firstly investigated.•The altered endogenous metabolites were closely related to SCFAs-producing and anti-inflammatory gut microflora.•Xiexin Dec...

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Veröffentlicht in:	Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Analytical technologies in the biomedical and life sciences, 2021-05, Vol.1173, p.122683-122683, Article 122683
Hauptverfasser:	Zhang, Zhi-Miao, Chen, Meng-Jun, Zou, Jun-Feng, Jiang, Shu, Shang, Er-Xin, Qian, Da-Wei, Duan, Jin-Ao
Format:	Artikel
Sprache:	eng
Schlagworte:	Metabolomics Type 2 diabetes mellitus UPLC-Q-TOF/MS Xiexin Decoction
Online-Zugang:	Volltext
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