Vaccine development for emerging infectious diseases

Examination of the vaccine strategies and technical platforms used for the COVID-19 pandemic in the context of those used for previous emerging and reemerging infectious diseases and pandemics may offer some mutually beneficial lessons. The unprecedented scale and rapidity of dissemination of recent...

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Veröffentlicht in:Nature medicine 2021-04, Vol.27 (4), p.591-600
Hauptverfasser: Excler, Jean-Louis, Saville, Melanie, Berkley, Seth, Kim, Jerome H.
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creator Excler, Jean-Louis
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Berkley, Seth
Kim, Jerome H.
description Examination of the vaccine strategies and technical platforms used for the COVID-19 pandemic in the context of those used for previous emerging and reemerging infectious diseases and pandemics may offer some mutually beneficial lessons. The unprecedented scale and rapidity of dissemination of recent emerging infectious diseases pose new challenges for vaccine developers, regulators, health authorities and political constituencies. Vaccine manufacturing and distribution are complex and challenging. While speed is essential, clinical development to emergency use authorization and licensure, pharmacovigilance of vaccine safety and surveillance of virus variants are also critical. Access to vaccines and vaccination needs to be prioritized in low- and middle-income countries. The combination of these factors will weigh heavily on the ultimate success of efforts to bring the current and any future emerging infectious disease pandemics to a close. Examination of the vaccine strategies and technical platforms used for the COVID-19 pandemic in the context of those used for previous emerging and reemerging infectious diseases and pandemics can offer critical lessons to prepare for future public health emergencies.
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subjects 631/250/590
692/699/255/2514
Biomedical and Life Sciences
Biomedicine
Cancer Research
Cholera Vaccines - immunology
Communicable Diseases, Emerging - epidemiology
Communicable Diseases, Emerging - prevention & control
Context
Coronaviruses
COVID-19
COVID-19 - prevention & control
COVID-19 vaccines
COVID-19 Vaccines - immunology
Dengue Vaccines - immunology
Emerging communicable diseases
Epidemics
Health Services Accessibility
Humans
Infectious Diseases
Metabolic Diseases
Molecular Medicine
Neurosciences
Pandemics
Pharmaceutical research
Pharmacovigilance
Platforms
Prevention
Public health
Regulators
Review Article
SARS-CoV-2 - immunology
South Korea
Typhoid-Paratyphoid Vaccines - immunology
Vaccine development
Vaccines
Vaccines - immunology
Viral diseases
Yellow Fever Vaccine - immunology
title Vaccine development for emerging infectious diseases
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