Vaccine development for emerging infectious diseases
Examination of the vaccine strategies and technical platforms used for the COVID-19 pandemic in the context of those used for previous emerging and reemerging infectious diseases and pandemics may offer some mutually beneficial lessons. The unprecedented scale and rapidity of dissemination of recent...
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Veröffentlicht in: | Nature medicine 2021-04, Vol.27 (4), p.591-600 |
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description | Examination of the vaccine strategies and technical platforms used for the COVID-19 pandemic in the context of those used for previous emerging and reemerging infectious diseases and pandemics may offer some mutually beneficial lessons. The unprecedented scale and rapidity of dissemination of recent emerging infectious diseases pose new challenges for vaccine developers, regulators, health authorities and political constituencies. Vaccine manufacturing and distribution are complex and challenging. While speed is essential, clinical development to emergency use authorization and licensure, pharmacovigilance of vaccine safety and surveillance of virus variants are also critical. Access to vaccines and vaccination needs to be prioritized in low- and middle-income countries. The combination of these factors will weigh heavily on the ultimate success of efforts to bring the current and any future emerging infectious disease pandemics to a close.
Examination of the vaccine strategies and technical platforms used for the COVID-19 pandemic in the context of those used for previous emerging and reemerging infectious diseases and pandemics can offer critical lessons to prepare for future public health emergencies. |
doi_str_mv | 10.1038/s41591-021-01301-0 |
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Examination of the vaccine strategies and technical platforms used for the COVID-19 pandemic in the context of those used for previous emerging and reemerging infectious diseases and pandemics can offer critical lessons to prepare for future public health emergencies.</description><identifier>ISSN: 1078-8956</identifier><identifier>EISSN: 1546-170X</identifier><identifier>DOI: 10.1038/s41591-021-01301-0</identifier><identifier>PMID: 33846611</identifier><language>eng</language><publisher>New York: Nature Publishing Group US</publisher><subject>631/250/590 ; 692/699/255/2514 ; Biomedical and Life Sciences ; Biomedicine ; Cancer Research ; Cholera Vaccines - immunology ; Communicable Diseases, Emerging - epidemiology ; Communicable Diseases, Emerging - prevention & control ; Context ; Coronaviruses ; COVID-19 ; COVID-19 - prevention & control ; COVID-19 vaccines ; COVID-19 Vaccines - immunology ; Dengue Vaccines - immunology ; Emerging communicable diseases ; Epidemics ; Health Services Accessibility ; Humans ; Infectious Diseases ; Metabolic Diseases ; Molecular Medicine ; Neurosciences ; Pandemics ; Pharmaceutical research ; Pharmacovigilance ; Platforms ; Prevention ; Public health ; Regulators ; Review Article ; SARS-CoV-2 - immunology ; South Korea ; Typhoid-Paratyphoid Vaccines - immunology ; Vaccine development ; Vaccines ; Vaccines - immunology ; Viral diseases ; Yellow Fever Vaccine - immunology</subject><ispartof>Nature medicine, 2021-04, Vol.27 (4), p.591-600</ispartof><rights>The Author(s), under exclusive licence to Springer Nature America, Inc. 2021</rights><rights>COPYRIGHT 2021 Nature Publishing Group</rights><rights>The Author(s), under exclusive licence to Springer Nature America, Inc. 2021.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c623t-b67fb71c67b1a56ccee897644034cdbbb46ada2199f61f7c82d799166003f80b3</citedby><cites>FETCH-LOGICAL-c623t-b67fb71c67b1a56ccee897644034cdbbb46ada2199f61f7c82d799166003f80b3</cites><orcidid>0000-0002-6462-5101 ; 0000-0003-0461-6438</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/s41591-021-01301-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/s41591-021-01301-0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,777,781,27905,27906,41469,42538,51300</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33846611$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Excler, Jean-Louis</creatorcontrib><creatorcontrib>Saville, Melanie</creatorcontrib><creatorcontrib>Berkley, Seth</creatorcontrib><creatorcontrib>Kim, Jerome H.</creatorcontrib><title>Vaccine development for emerging infectious diseases</title><title>Nature medicine</title><addtitle>Nat Med</addtitle><addtitle>Nat Med</addtitle><description>Examination of the vaccine strategies and technical platforms used for the COVID-19 pandemic in the context of those used for previous emerging and reemerging infectious diseases and pandemics may offer some mutually beneficial lessons. The unprecedented scale and rapidity of dissemination of recent emerging infectious diseases pose new challenges for vaccine developers, regulators, health authorities and political constituencies. Vaccine manufacturing and distribution are complex and challenging. While speed is essential, clinical development to emergency use authorization and licensure, pharmacovigilance of vaccine safety and surveillance of virus variants are also critical. Access to vaccines and vaccination needs to be prioritized in low- and middle-income countries. The combination of these factors will weigh heavily on the ultimate success of efforts to bring the current and any future emerging infectious disease pandemics to a close.
Examination of the vaccine strategies and technical platforms used for the COVID-19 pandemic in the context of those used for previous emerging and reemerging infectious diseases and pandemics can offer critical lessons to prepare for future public health emergencies.</description><subject>631/250/590</subject><subject>692/699/255/2514</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Cancer Research</subject><subject>Cholera Vaccines - immunology</subject><subject>Communicable Diseases, Emerging - epidemiology</subject><subject>Communicable Diseases, Emerging - prevention & control</subject><subject>Context</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>COVID-19 - prevention & control</subject><subject>COVID-19 vaccines</subject><subject>COVID-19 Vaccines - immunology</subject><subject>Dengue Vaccines - immunology</subject><subject>Emerging communicable diseases</subject><subject>Epidemics</subject><subject>Health Services Accessibility</subject><subject>Humans</subject><subject>Infectious Diseases</subject><subject>Metabolic Diseases</subject><subject>Molecular Medicine</subject><subject>Neurosciences</subject><subject>Pandemics</subject><subject>Pharmaceutical research</subject><subject>Pharmacovigilance</subject><subject>Platforms</subject><subject>Prevention</subject><subject>Public health</subject><subject>Regulators</subject><subject>Review Article</subject><subject>SARS-CoV-2 - 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Academic</collection><jtitle>Nature medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Excler, Jean-Louis</au><au>Saville, Melanie</au><au>Berkley, Seth</au><au>Kim, Jerome H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Vaccine development for emerging infectious diseases</atitle><jtitle>Nature medicine</jtitle><stitle>Nat Med</stitle><addtitle>Nat Med</addtitle><date>2021-04-01</date><risdate>2021</risdate><volume>27</volume><issue>4</issue><spage>591</spage><epage>600</epage><pages>591-600</pages><issn>1078-8956</issn><eissn>1546-170X</eissn><abstract>Examination of the vaccine strategies and technical platforms used for the COVID-19 pandemic in the context of those used for previous emerging and reemerging infectious diseases and pandemics may offer some mutually beneficial lessons. The unprecedented scale and rapidity of dissemination of recent emerging infectious diseases pose new challenges for vaccine developers, regulators, health authorities and political constituencies. Vaccine manufacturing and distribution are complex and challenging. While speed is essential, clinical development to emergency use authorization and licensure, pharmacovigilance of vaccine safety and surveillance of virus variants are also critical. Access to vaccines and vaccination needs to be prioritized in low- and middle-income countries. The combination of these factors will weigh heavily on the ultimate success of efforts to bring the current and any future emerging infectious disease pandemics to a close.
Examination of the vaccine strategies and technical platforms used for the COVID-19 pandemic in the context of those used for previous emerging and reemerging infectious diseases and pandemics can offer critical lessons to prepare for future public health emergencies.</abstract><cop>New York</cop><pub>Nature Publishing Group US</pub><pmid>33846611</pmid><doi>10.1038/s41591-021-01301-0</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0002-6462-5101</orcidid><orcidid>https://orcid.org/0000-0003-0461-6438</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | 631/250/590 692/699/255/2514 Biomedical and Life Sciences Biomedicine Cancer Research Cholera Vaccines - immunology Communicable Diseases, Emerging - epidemiology Communicable Diseases, Emerging - prevention & control Context Coronaviruses COVID-19 COVID-19 - prevention & control COVID-19 vaccines COVID-19 Vaccines - immunology Dengue Vaccines - immunology Emerging communicable diseases Epidemics Health Services Accessibility Humans Infectious Diseases Metabolic Diseases Molecular Medicine Neurosciences Pandemics Pharmaceutical research Pharmacovigilance Platforms Prevention Public health Regulators Review Article SARS-CoV-2 - immunology South Korea Typhoid-Paratyphoid Vaccines - immunology Vaccine development Vaccines Vaccines - immunology Viral diseases Yellow Fever Vaccine - immunology |
title | Vaccine development for emerging infectious diseases |
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