Xylogalacturonan-enriched pectin from the fruit pulp of Adansonia digitata: Structural characterization and antidepressant-like effect
[Display omitted] •Xylogalacturonan-enriched pectin is water-soluble pectin from the baobab fruit pulp.•Starch is co-extracted with pectin at long extraction times and temperatures.•Part of α-GalpA residues are 3-O-substituted with terminal β-Xylp residues.•Xylogalacturonan possesses an antidepressa...
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| Veröffentlicht in: | Carbohydrate polymers 2021-06, Vol.262, p.117946-117946, Article 117946 |
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| container_title | Carbohydrate polymers |
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| creator | Patova, O.A. Luаnda, A. Paderin, N.M. Popov, S.V. Makangara, J.J. Kuznetsov, S.P. Kalmykova, E.N. |
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•Xylogalacturonan-enriched pectin is water-soluble pectin from the baobab fruit pulp.•Starch is co-extracted with pectin at long extraction times and temperatures.•Part of α-GalpA residues are 3-O-substituted with terminal β-Xylp residues.•Xylogalacturonan possesses an antidepressant-like effect.
The low methyl-esterified and acetylated xylogalacturonan (DM 20 %, DA 2 %, Mw ∼ 58 kDa) was isolated by water extraction for 4 h × 2 at 50 °C (yield 23 %) from the pulp of baobab fruit (Adansonia digitata L.). Subsequent tightening of the conditions for water extraction by mean increasing the temperature to 70 °C and time to 12 h led to the co-extraction of small amounts of starch components and RG I with xylogalacturonan. Structural analysis (DEAE-cellulose ion-exchange chromatography, HPSEC, monosaccharide analysis, NMR spectroscopy) revealed that about 12 mol. % of 1,4-linked α-GalpA residues were substituted by single β-Xylp residues at the O-3 position. The xylogalacturonan was found to possess an antidepressant-like effect in mice. The study offers using the baobab fruit as a rich source of soluble dietary fiber – water-soluble pectin with beneficial physiological effect. |
| doi_str_mv | 10.1016/j.carbpol.2021.117946 |
| format | Article |
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•Xylogalacturonan-enriched pectin is water-soluble pectin from the baobab fruit pulp.•Starch is co-extracted with pectin at long extraction times and temperatures.•Part of α-GalpA residues are 3-O-substituted with terminal β-Xylp residues.•Xylogalacturonan possesses an antidepressant-like effect.
The low methyl-esterified and acetylated xylogalacturonan (DM 20 %, DA 2 %, Mw ∼ 58 kDa) was isolated by water extraction for 4 h × 2 at 50 °C (yield 23 %) from the pulp of baobab fruit (Adansonia digitata L.). Subsequent tightening of the conditions for water extraction by mean increasing the temperature to 70 °C and time to 12 h led to the co-extraction of small amounts of starch components and RG I with xylogalacturonan. Structural analysis (DEAE-cellulose ion-exchange chromatography, HPSEC, monosaccharide analysis, NMR spectroscopy) revealed that about 12 mol. % of 1,4-linked α-GalpA residues were substituted by single β-Xylp residues at the O-3 position. The xylogalacturonan was found to possess an antidepressant-like effect in mice. The study offers using the baobab fruit as a rich source of soluble dietary fiber – water-soluble pectin with beneficial physiological effect.</description><identifier>ISSN: 0144-8617</identifier><identifier>EISSN: 1879-1344</identifier><identifier>DOI: 10.1016/j.carbpol.2021.117946</identifier><identifier>PMID: 33838823</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Baobab ; Biological activity ; NMR ; Polysaccharide isolation</subject><ispartof>Carbohydrate polymers, 2021-06, Vol.262, p.117946-117946, Article 117946</ispartof><rights>2021 Elsevier Ltd</rights><rights>Copyright © 2021 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c365t-96e2f15afeee49961b5b25873a5f44af6298bb08b5dcf81a3a7731578af133853</citedby><cites>FETCH-LOGICAL-c365t-96e2f15afeee49961b5b25873a5f44af6298bb08b5dcf81a3a7731578af133853</cites><orcidid>0000-0001-5236-4867 ; 0000-0003-1763-8898</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.carbpol.2021.117946$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,45974</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33838823$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Patova, O.A.</creatorcontrib><creatorcontrib>Luаnda, A.</creatorcontrib><creatorcontrib>Paderin, N.M.</creatorcontrib><creatorcontrib>Popov, S.V.</creatorcontrib><creatorcontrib>Makangara, J.J.</creatorcontrib><creatorcontrib>Kuznetsov, S.P.</creatorcontrib><creatorcontrib>Kalmykova, E.N.</creatorcontrib><title>Xylogalacturonan-enriched pectin from the fruit pulp of Adansonia digitata: Structural characterization and antidepressant-like effect</title><title>Carbohydrate polymers</title><addtitle>Carbohydr Polym</addtitle><description>[Display omitted]
•Xylogalacturonan-enriched pectin is water-soluble pectin from the baobab fruit pulp.•Starch is co-extracted with pectin at long extraction times and temperatures.•Part of α-GalpA residues are 3-O-substituted with terminal β-Xylp residues.•Xylogalacturonan possesses an antidepressant-like effect.
The low methyl-esterified and acetylated xylogalacturonan (DM 20 %, DA 2 %, Mw ∼ 58 kDa) was isolated by water extraction for 4 h × 2 at 50 °C (yield 23 %) from the pulp of baobab fruit (Adansonia digitata L.). Subsequent tightening of the conditions for water extraction by mean increasing the temperature to 70 °C and time to 12 h led to the co-extraction of small amounts of starch components and RG I with xylogalacturonan. Structural analysis (DEAE-cellulose ion-exchange chromatography, HPSEC, monosaccharide analysis, NMR spectroscopy) revealed that about 12 mol. % of 1,4-linked α-GalpA residues were substituted by single β-Xylp residues at the O-3 position. The xylogalacturonan was found to possess an antidepressant-like effect in mice. The study offers using the baobab fruit as a rich source of soluble dietary fiber – water-soluble pectin with beneficial physiological effect.</description><subject>Baobab</subject><subject>Biological activity</subject><subject>NMR</subject><subject>Polysaccharide isolation</subject><issn>0144-8617</issn><issn>1879-1344</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNqFUcGKFDEQDaK4s6ufoOTopcdOJ-lOe5Fl0VVY8KCCt1CdVHYy9iRtkhbWD_C7zTCjVwuKqsOr93j1CHnB2i1rWf96vzWQpiXO267t2JaxYRT9I7JhahgbxoV4TDYtE6JRPRsuyGXO-7ZWz9qn5IJzxZXq-Ib8_vYwx3uYwZQ1xQChwZC82aGlC5riA3UpHmjZYV1WX-iyzguNjl5bCDkGD9T6e1-gwBv6uaT1yAMzNTtIlROT_wXFx0Ah2NrFW1wS5lzXZvbfkaJzVecZeeJgzvj8PK_I1_fvvtx8aO4-3X68ub5rDO9lacYeO8ckOEQU49izSU6dVAMH6YQA13ejmqZWTdIapxhwGAbO5KDAsepZ8ivy6sS7pPhjxVz0wWeD8wwB45p1JxlTo-CDqFB5gpoUc07o9JL8AdKDZq0-RqD3-hyBPkagTxHUu5dniXU6oP139ffnFfD2BMBq9KfHpLPxGAxan-ortI3-PxJ_AKLynZA</recordid><startdate>20210615</startdate><enddate>20210615</enddate><creator>Patova, O.A.</creator><creator>Luаnda, A.</creator><creator>Paderin, N.M.</creator><creator>Popov, S.V.</creator><creator>Makangara, J.J.</creator><creator>Kuznetsov, S.P.</creator><creator>Kalmykova, E.N.</creator><general>Elsevier Ltd</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-5236-4867</orcidid><orcidid>https://orcid.org/0000-0003-1763-8898</orcidid></search><sort><creationdate>20210615</creationdate><title>Xylogalacturonan-enriched pectin from the fruit pulp of Adansonia digitata: Structural characterization and antidepressant-like effect</title><author>Patova, O.A. ; Luаnda, A. ; Paderin, N.M. ; Popov, S.V. ; Makangara, J.J. ; Kuznetsov, S.P. ; Kalmykova, E.N.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c365t-96e2f15afeee49961b5b25873a5f44af6298bb08b5dcf81a3a7731578af133853</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Baobab</topic><topic>Biological activity</topic><topic>NMR</topic><topic>Polysaccharide isolation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Patova, O.A.</creatorcontrib><creatorcontrib>Luаnda, A.</creatorcontrib><creatorcontrib>Paderin, N.M.</creatorcontrib><creatorcontrib>Popov, S.V.</creatorcontrib><creatorcontrib>Makangara, J.J.</creatorcontrib><creatorcontrib>Kuznetsov, S.P.</creatorcontrib><creatorcontrib>Kalmykova, E.N.</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Carbohydrate polymers</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Patova, O.A.</au><au>Luаnda, A.</au><au>Paderin, N.M.</au><au>Popov, S.V.</au><au>Makangara, J.J.</au><au>Kuznetsov, S.P.</au><au>Kalmykova, E.N.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Xylogalacturonan-enriched pectin from the fruit pulp of Adansonia digitata: Structural characterization and antidepressant-like effect</atitle><jtitle>Carbohydrate polymers</jtitle><addtitle>Carbohydr Polym</addtitle><date>2021-06-15</date><risdate>2021</risdate><volume>262</volume><spage>117946</spage><epage>117946</epage><pages>117946-117946</pages><artnum>117946</artnum><issn>0144-8617</issn><eissn>1879-1344</eissn><abstract>[Display omitted]
•Xylogalacturonan-enriched pectin is water-soluble pectin from the baobab fruit pulp.•Starch is co-extracted with pectin at long extraction times and temperatures.•Part of α-GalpA residues are 3-O-substituted with terminal β-Xylp residues.•Xylogalacturonan possesses an antidepressant-like effect.
The low methyl-esterified and acetylated xylogalacturonan (DM 20 %, DA 2 %, Mw ∼ 58 kDa) was isolated by water extraction for 4 h × 2 at 50 °C (yield 23 %) from the pulp of baobab fruit (Adansonia digitata L.). Subsequent tightening of the conditions for water extraction by mean increasing the temperature to 70 °C and time to 12 h led to the co-extraction of small amounts of starch components and RG I with xylogalacturonan. Structural analysis (DEAE-cellulose ion-exchange chromatography, HPSEC, monosaccharide analysis, NMR spectroscopy) revealed that about 12 mol. % of 1,4-linked α-GalpA residues were substituted by single β-Xylp residues at the O-3 position. The xylogalacturonan was found to possess an antidepressant-like effect in mice. The study offers using the baobab fruit as a rich source of soluble dietary fiber – water-soluble pectin with beneficial physiological effect.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>33838823</pmid><doi>10.1016/j.carbpol.2021.117946</doi><tpages>1</tpages><orcidid>https://orcid.org/0000-0001-5236-4867</orcidid><orcidid>https://orcid.org/0000-0003-1763-8898</orcidid></addata></record> |
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| subjects | Baobab Biological activity NMR Polysaccharide isolation |
| title | Xylogalacturonan-enriched pectin from the fruit pulp of Adansonia digitata: Structural characterization and antidepressant-like effect |
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