The chromatin remodeler DDM1 prevents transposon mobility through deposition of histone variant H2A.W

Mobile transposable elements (TEs) not only participate in genome evolution but also threaten genome integrity. In healthy cells, TEs that encode all of the components that are necessary for their mobility are specifically silenced, yet the precise mechanism remains unknown. Here, we characterize th...

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Veröffentlicht in:	Nature cell biology 2021-04, Vol.23 (4), p.391-400
Hauptverfasser:	Osakabe, Akihisa, Jamge, Bhagyshree, Axelsson, Elin, Montgomery, Sean A., Akimcheva, Svetlana, Kuehn, Annika Luisa, Pisupati, Rahul, Lorković, Zdravko J., Yelagandula, Ramesh, Kakutani, Tetsuji, Berger, Frédéric
Format:	Artikel
Sprache:	eng
Schlagworte:	38 38/22 38/39 45 45/15 45/22 45/23 45/90 631/208/176 631/208/211 631/337/100/102 631/45/612/100 82 82/51 82/83 Arabidopsis Arabidopsis - genetics Arabidopsis Proteins - genetics Biomedical and Life Sciences Cancer Research Cell Biology Chromatin Chromatin - genetics Chromatin Assembly and Disassembly - genetics Deoxyribonucleic acid Deposition Developmental Biology DNA DNA methylation DNA Methylation - genetics DNA Transposable Elements - genetics DNA-Binding Proteins - genetics Evolution Evolution, Molecular Gene Expression Regulation, Plant - genetics Gene Silencing Genetic aspects Genetic research Genome, Plant - genetics Genomes Heterochromatin Heterochromatin - genetics Histones Histones - genetics Life Sciences Mobility Plant molecular genetics Stem Cells Structure Transcription Factors - genetics Transposons
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