Carpal Tunnel Syndrome Due to Iatrogenic Amyloidosis After Domino Liver Transplantation From Hereditary Transthyretin Amyloidosis: A Case Report

Carpal Tunnel Syndrome Due to Iatrogenic Amyloidosis After Domino Liver Transplantation From Hereditary Transthyretin Amyloidosis: A Case Report

Carpal tunnel syndrome is the most common compression syndrome of the peripheral nerve. Transthyretin amyloidosis and dialysis-related β2-microglobulin amyloidosis are known causes of carpal tunnel syndrome. A Japanese woman showed carpal tunnel syndrome 16 years after a domino liver transplantation...

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Veröffentlicht in:Transplantation proceedings 2021-05, Vol.53 (4), p.1313-1316
Hauptverfasser: Ohya, Yuki, Tasaki, Masayoshi, Hayashida, Shintaro, Katayama, Nobuhiro, Tsuchida, Toru, Kuriwaki, Kazumi, Ueda, Mitsuharu, Inomata, Yukihiro
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container_end_page 1316
container_issue 4
container_start_page 1313
container_title Transplantation proceedings
container_volume 53
creator Ohya, Yuki
Tasaki, Masayoshi
Hayashida, Shintaro
Katayama, Nobuhiro
Tsuchida, Toru
Kuriwaki, Kazumi
Ueda, Mitsuharu
Inomata, Yukihiro
description Carpal tunnel syndrome is the most common compression syndrome of the peripheral nerve. Transthyretin amyloidosis and dialysis-related β2-microglobulin amyloidosis are known causes of carpal tunnel syndrome. A Japanese woman showed carpal tunnel syndrome 16 years after a domino liver transplantation (DLT) from the donor with hereditary transthyretin amyloidosis. DLT indication was congenital extrahepatic portosystemic shunt, and the patient had been put on maintenance hemodialysis because of chronic kidney disease 6 years before DLT. Moreover, the amyloid precursor protein of the patient was histologically confirmed not to be β2-microglobulin, but transthyretin. The existence of amyloid was speculated when the patient who underwent DLT from hereditary transthyretin amyloidosis showed carpal tunnel syndrome. Additionally, elucidating the amyloid precursor protein when the patient has another cause of amyloidosis is necessary.
doi_str_mv 10.1016/j.transproceed.2021.03.001
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title Carpal Tunnel Syndrome Due to Iatrogenic Amyloidosis After Domino Liver Transplantation From Hereditary Transthyretin Amyloidosis: A Case Report
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