Association of interleukin-12B rs6887695 with susceptibility to allergic rhinitis

Interleukin-12 (IL-12) is a heterodimeric cytokine encoded by two separate genes, IL12A and IL12B, which may play a regulatory role in allergen-induced inflammation through CD4 + T-cell subsets polarization. The aim of this study was to investigate the association of single-nucleotide polymorphisms...

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Veröffentlicht in:	Immunologic research 2021-04, Vol.69 (2), p.189-195
Hauptverfasser:	Falahi, Sara, Salari, Farhad, Rezaiemanesh, Alireza, Mortazavi, Seyed Hamidreza, Koohyanizadeh, Farzaneh, Lotfi, Ramin, Gorgin Karaji, Ali
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Allergens Allergic rhinitis Allergology Biomarkers Biomedical and Life Sciences Biomedicine Case-Control Studies CD4 antigen Cytokines Female Gene polymorphism Genetic Predisposition to Disease Genotype Haplotypes Humans IL12B protein Immunology Inflammation Interleukin 1 Interleukin 12 Interleukin-12 Subunit p40 - genetics Internal Medicine Iran Lymphocytes T Male Medicine/Public Health Middle Aged Nucleotides Original Article Polymerase chain reaction Polymorphism Polymorphism, Single Nucleotide Restriction fragment length polymorphism Rhinitis Rhinitis, Allergic - genetics Single-nucleotide polymorphism Statistical analysis Susceptibility
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