Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2

Specification of the progenitors’ regional identity is a pivotal step during development of the cerebral cortex and basal ganglia. The molecular mechanisms underlying progenitor regionalization, however, are poorly understood. Here we showed that the transcription factor Vax1 was highly expressed in...

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Veröffentlicht in:	Molecular neurobiology 2021-08, Vol.58 (8), p.3729-3744
Hauptverfasser:	Wen, Yan, Su, Zihao, Wang, Ziwu, Yang, Lin, Liu, Guoping, Shang, Zicong, Duan, Yangyang, Du, Heng, Li, Zhenmeiyu, You, Yan, Li, Xiaosu, Yang, Zhengang, Zhang, Zhuangzhi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Basal ganglia Biomedical and Life Sciences Biomedicine Cell Biology Cell proliferation Cerebral cortex Corpus Striatum - cytology Corpus Striatum - embryology Corpus Striatum - metabolism Globus Pallidus - cytology Globus Pallidus - embryology Globus Pallidus - metabolism Homeodomain Proteins - antagonists & inhibitors Homeodomain Proteins - biosynthesis Homeodomain Proteins - genetics Hybridization Immunofluorescence Mice Mice, Inbred C57BL Mice, Transgenic Molecular modelling Neural stem cells Neural Stem Cells - metabolism Neurobiology Neurogenesis - physiology Neurology Neuropeptides - biosynthesis Neuropeptides - genetics Neurosciences Progenitor cells Septum Transcription factors
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