STAT3 activates the transcription of lncRNA NR2F1-AS1 to promote the progression of melanoma via regulating the miR-493-5p/GOLM1 axis

Long non-coding RNAs (lncRNAs) are vital regulators during the biological processes of melanoma. The present study aimed to uncover biological functions of lncRNA termed NR2F1 antisense RNA 1 (NR2F1-AS1) in melanoma and the potential mechanisms. Relative levels of NR2F1-AS1 and miR-493-5p in a total...

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Veröffentlicht in:	The journal of gene medicine 2021-07, Vol.23 (7), p.e3338-e3338
Hauptverfasser:	Bai, Mei, Wu, Zong-Zhou, Huang, Yan-Li, Ke, Jin, Xu, Qing, Wang, Xiong
Format:	Artikel
Sprache:	eng
Schlagworte:	Antisense RNA Cell Line, Tumor Cell migration Cell Movement Cell Proliferation Cholecystokinin Chromatin COUP Transcription Factor I - genetics COUP Transcription Factor I - metabolism Disease Progression Gene Expression Regulation, Neoplastic Gene therapy Humans Immunoprecipitation Melanoma Melanoma - genetics Melanoma - metabolism Membrane Proteins - metabolism MicroRNAs - metabolism Non-coding RNA Polymerase chain reaction RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism Signal Transduction Stat3 protein STAT3 Transcription Factor - genetics Transcription Tumorigenesis Wound healing
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