Improved biotechnological production of paclitaxel in Taxus media cell cultures by the combined action of coronatine and calix[8]arenes

Paclitaxel (PTX), a widely used anticancer agent, is found in the inner bark of several Taxus species, although at such low levels that its extraction is ecologically unsustainable. Biotechnological platforms based on Taxus sp. cell cultures offer an eco-friendlier approach to PTX production, with y...

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Veröffentlicht in:	Plant physiology and biochemistry 2021-06, Vol.163, p.68-75
Hauptverfasser:	Escrich, Ainoa, Almagro, Lorena, Moyano, Elisabeth, Cusido, Rosa M., Bonfill, Mercedes, Hosseini, Bahman, Palazon, Javier
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids Calixarenes Cell Culture Techniques Cells, Cultured Coronatine Gene expression Indenes Paclitaxel Paclitaxel - pharmacology Taxane production Taxus Taxus cell cultures
Online-Zugang:	Volltext
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