Squamosamide Derivative FLZ Diminishes Aberrant Mitochondrial Fission by Inhibiting Dynamin-Related Protein 1

Mitochondrial dysfunction is involved in the pathogenesis of Parkinson's disease (PD). Mitochondrial morphology is dynamic and precisely regulated by mitochondrial fission and fusion machinery. Aberrant mitochondrial fragmentation, which can result in cell death, is controlled by the mitochondr...

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Veröffentlicht in:Frontiers in pharmacology 2021-03, Vol.12, p.588003-588003
Hauptverfasser: Yang, Hanyu, Wang, Lu, Zang, Caixia, Yang, Xu, Bao, Xiuqi, Shang, Junmei, Zhang, Zihong, Liu, Hui, Ju, Cheng, Li, Fangyuan, Yuan, Fangyu, Zhang, Dan
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