Efficient photodynamic inactivation of Leishmania parasites mediated by lipophilic water-soluble Zn(II) porphyrin ZnTnHex-2-PyP4

Photodynamic inactivation (PDI) is emerging as a promising alternative for cutaneous leishmaniasis (CL). The chemotherapy currently used presents adverse effects and cases of drug resistance have been reported. ZnTnHex-2-PyP4+ is a porphyrin with a high potential as a photosensitizer (PS) for PDI, d...

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Veröffentlicht in:	Biochimica et biophysica acta. General subjects 2021-07, Vol.1865 (7), p.129897-129897, Article 129897
Hauptverfasser:	Souza, Tiago H.S., Andrade, Camila G., Cabral, Fernanda V., Sarmento-Neto, José F., Rebouças, Júlio S., Santos, Beate S., Ribeiro, Martha S., Figueiredo, Regina C.B.Q., Fontes, Adriana
Format:	Artikel
Sprache:	eng
Schlagworte:	Antimicrobial photodynamic therapy Blue LED Leishmania amazonensis Leishmania braziliensis Photodynamic therapy ZnTnHex-2-PyP4
Online-Zugang:	Volltext
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