Extracellular matrix influences astrocytic extracellular vesicle function in wound repair

•ECM substrates influence astrocyte wound recovery through astrocytic EV release.•β1 integrin mediates ECM dependent astrocyte wound responses.•IL-1β influences astrocytic wound response to mechanical injury. Astrocytic injury responses are known to be influenced by the extracellular matrix (ECM). A...

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Veröffentlicht in:	Brain research 2021-07, Vol.1763, p.147462-147462, Article 147462
Hauptverfasser:	Sutter, Pearl A., Rouillard, Megan E., Alshawi, Sarah A., Crocker, Stephen J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Astrocyte Astrocytes - physiology Extracellular matrix Extracellular Matrix - physiology Extracellular vesicle Extracellular Vesicles - physiology IL-1β Integrin Integrin beta1 - metabolism Interleukin-1beta - metabolism Mice Mice, Inbred C57BL Scratch wound Wound Healing - physiology
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