Phosphatidylinositol 3-kinase gamma participates in nimesulide-induced hepatic damage

Abstract Objective To evaluate the participation of the phosphatidylinositol 3-kinase pathway in the liver damage caused by nimesulide. Methods Liver damage been induced by nimesulide. Mice were treated with either 2% dimethyl sulfoxide or AS605240, a phosphatidylinositol 3-kinase gamma pathway anta...

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Veröffentlicht in:	Journal of pharmacy and pharmacology 2021-03, Vol.73 (4), p.496-504
Hauptverfasser:	Pereira, Cynthia Maria C, Júnior, Genilson José Dias, Lima, José Victor do N, Alves Lemos, Sarah Izabelly, da Rocha Rodrigues, Lauanda, dos Santos Ferreira, Jayro, Araújo, Anna Sofia Miranda Loiola, de Oliveira, Joveline Costa, Monteiro, Carlos Eduardo, Franco, Álvaro Xavier, Pereira Alves, Even Herlany, Oliveira Silva, Francisca Géssica, de Carvalho Filgueiras, Marcelo, Soares, Pedro M G, Pereira Vasconcelos, Daniel Fernando, de Oliveira, Jefferson Soares, de Brito, Tarcisio Vieira, Barbosa, André Luiz Reis
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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