Examination of the Antimicrobial Peptide Myticalin A6 Active Site

In 2017, Leoni et al. reported myticalins as novel cationic linear antimicrobial peptides obtained from marine mussels. The authors focused on myticalin A6 (29 amino acids), which has a relatively short chain length among myticalins and contains a repeating X-proline(Pro)-arginine (Arg) sequence in...

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Veröffentlicht in:	Biological & pharmaceutical bulletin 2021/04/01, Vol.44(4), pp.515-521
Hauptverfasser:	Okimura, Keiko, Matsubara, Keiko, Suzuki, Rie, Ito, Hanako, Sato, Ayumi, Sugimoto, Kaori
Format:	Artikel
Sprache:	eng
Schlagworte:	active site Amino acids Antimicrobial activity Antimicrobial agents Antimicrobial peptides Arginine Aspartic acid Circular dichroism circular dichroism spectroscopy cyclic peptide Lysine myticalin A6 derivative Proline Protein structure Secondary structure Spectroscopy Staphylococcus aureus
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