Progression‐free survival in oncological clinical studies: Assessment time bias and methods for its correction

Progression‐free survival (PFS) is a frequently used endpoint in oncological clinical studies. In case of PFS, potential events are progression and death. Progressions are usually observed delayed as they can be diagnosed not before the next study visit. For this reason potential bias of treatment e...

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Veröffentlicht in:	Pharmaceutical statistics : the journal of the pharmaceutical industry 2021-07, Vol.20 (4), p.864-878
Hauptverfasser:	Miltenberger, Robert, Götte, Heiko, Schüler, Armin, Jahn‐Eimermacher, Antje
Format:	Artikel
Sprache:	eng
Schlagworte:	approximate Bayesian computation Bias bias correction interval censoring progression‐free survival Weibull distribution
Online-Zugang:	Volltext
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