Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization
Glioblastomas are aggressive primary brain cancers that recur as therapy-resistant tumors. Myeloid cells control glioblastoma malignancy, but their dynamics during disease progression remain poorly understood. Here, we employed single-cell RNA sequencing and CITE-seq to map the glioblastoma immune l...
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Veröffentlicht in: | Nature neuroscience 2021-04, Vol.24 (4), p.595-610 |
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