Can polyunsaturated fatty acids regulate Polycystic Ovary Syndrome via TGF-β signalling?

Polycystic Ovary Syndrome (PCOS) is a metabolic condition that affects women in their reproductive age by altering the ovarian hormone levels, leading to infertility. Increased inflammation, insulin resistance, hyperandrogenism, irregular menses, and infertility are the causes of morbidity when PCOS...

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Veröffentlicht in:	Life sciences (1973) 2021-07, Vol.276, p.119416-119416, Article 119416
Hauptverfasser:	D. Prabhu, Yogamaya, Valsala Gopalakrishnan, Abilash
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiponectin Animals Chemical compounds Complications diabetes Diabetes mellitus drug therapy Extracellular matrix Fatty acids Fatty Acids, Unsaturated - metabolism Female Fibrillin fibrillins genes Growth factors Hormones Humans hyperandrogenism Infertility Inflammation Insulin Insulin resistance Menstrual cycle menstruation Metabolism Morbidity Mutation obesity Ovaries Pathogenesis Pharmacology Polycystic Ovary Syndrome Polycystic Ovary Syndrome - metabolism Polycystic Ovary Syndrome - pathology Polyunsaturated fatty acids Signal transduction Signaling Testosterone Therapeutic Transforming Growth Factor beta - metabolism Transforming growth factor-b Transforming Growth Factor-β
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