Development of an antibody-like T-cell engager based on VH-VL heterodimer formation and its application in cancer therapy

Following the clinical success of immunotherapeutic antibodies, bispecific antibodies for cytotoxic effector cell redirection, tumor-targeted immunomodulation and dual immunomodulation, have received particular attentions. Here, we developed a novel bispecific antibody platform, termed Antibody-Like...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biomaterials 2021-04, Vol.271, p.120760-120760, Article 120760
Hauptverfasser:	Jang, Seil, Song, Jaeho, Kim, NaYoung, Bak, Jeonghyeon, Jung, Keehoon, Park, Young Woo, Park, Bum-Chan, Kim, Ho Min
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibody-engineering Bispecific antibody Cancer immunotherapy T-cell engager
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!