Myeloablative versus Reduced-Intensity Conditioning for Hematopoietic Cell Transplantation in Acute Myelogenous Leukemia and Myelodysplastic Syndromes—Long-Term Follow-Up of the BMT CTN 0901 Clinical Trial

•There was a higher rate of treatment-related mortality with myeloablative conditioning, but this was offset by a much higher rate of relapse with reduced-intensity conditioning.•There was no difference in survival following relapse based on conditioning intensity.•Myeloablative conditioning led to...

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Veröffentlicht in:	Transplantation and cellular therapy 2021-06, Vol.27 (6), p.483.e1-483.e6
Hauptverfasser:	Scott, Bart L., Pasquini, Marcelo C., Fei, Mingwei, Fraser, Raphael, Wu, Juan, Devine, Steve M., Porter, David L., Maziarz, Richard T., Warlick, Erica, Fernandez, Hugo F., Soiffer, Robert J., Alyea, Edwin, Hamadani, Mehdi, Bashey, Asad, Giralt, Sergio, Geller, Nancy L., Leifer, Eric, Hourigan, Christopher S., Gui, Gege, Mendizabal, Adam, Horowitz, Mary M., Deeg, H. Joachim, Horwitz, Mitchell E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute myelogenous leukemia Adolescent Adult Aged Conditioning intensity Diterpenes Follow-Up Studies Hematopoietic cell transplantation Hematopoietic Stem Cell Transplantation Humans Leukemia, Myeloid, Acute - therapy Middle Aged Myelodysplastic syndrome Myelodysplastic Syndromes - therapy Prospective Studies Transplantation Conditioning Transplantation, Homologous Young Adult
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