Nifuroxazide as JAK2 inhibitor: A binding mode proposal and Hel cell proliferation assay

Nifuroxazide has been employed as an anti-diarrheic agent since 1966, but in the last decade has brought to the research spotlight again due to its recently described antitumoral activity through the JAK2 inhibitory potential. Since 2008, more than 70 papers have been published about the issue and m...

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Veröffentlicht in:	European journal of pharmaceutical sciences 2021-07, Vol.162, p.105822-105822, Article 105822
Hauptverfasser:	da Costa, Marcela Oliveira Legramanti, Pavani, Thais Fernanda Amorim, Lima, Angélica Nakagawa, Scott, Ana Lígia, Ramos, Débora Felicia Vieira, Lazarini, Mariana, Rando, Daniela Gonçales Galasse
Format:	Artikel
Sprache:	eng
Schlagworte:	Hell cells JAK/STAT Molecular Docking Molecular Dynamics Nifuroxazide
Online-Zugang:	Volltext
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