Nasopharyngeal carriage of otitis media pathogens in infants receiving 10-valent non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV10), 13-valent pneumococcal conjugate vaccine (PCV13) or a mixed primary schedule of both vaccines: A randomised controlled trial

Aboriginal children in Northern Australia have a high burden of otitis media, driven by early and persistent nasopharyngeal carriage of otopathogens, including non-typeable Haemophilus influenzae (NTHi) and Streptococcus pneumoniae (Spn). In this context, does a combined mixed primary series of Synf...

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Veröffentlicht in:	Vaccine 2021-04, Vol.39 (16), p.2264-2273
Hauptverfasser:	Beissbarth, J., Wilson, N., Arrowsmith, B., Binks, M.J., Oguoma, V.M., Lawrence, K., Llewellyn, A., Mulholland, E.K., Santosham, M., Morris, P.S., Smith-Vaughan, H.C., Cheng, A.C., Leach, A.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Antimicrobial agents Babies Carriage Children & youth Colonization Conjugates Discharge Ear diseases Ears & hearing Ethics Haemophilus influenzae Indigenous Infant Infants Membranes Mixed primary schedule Morphology Nasopharyngeal Native peoples Non-typeable Haemophilus influenza Otitis media Pathogens PCV13 Perforation PHiD-CV10 Pneumococcal conjugate vaccine Protein D Schedules Serotypes Statistical analysis Streptococcus infections Streptococcus pneumoniae Tympanic membrane Vaccines
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