4D spatiotemporal modulation of biomolecules distribution in anisotropic corrugated microwrinkles via electrically manipulated microcapsules within hierarchical hydrogel for spinal cord regeneration

Although traditional 3D scaffolds or biomimetic hydrogels have been used for tissue engineering and regenerative medicine, soft tissue microenvironment usually has a highly anisotropic structure and a dynamically controllable deformation with various biomolecule distribution. In this study, we devel...

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Veröffentlicht in:	Biomaterials 2021-04, Vol.271, p.120762-120762, Article 120762
Hauptverfasser:	Chiang, Min-Yu, Cheng, Hung-Wei, Lo, Yu-Chih, Wang, Wei-Chun, Chang, Shwu-Jen, Cheng, Chu-Hsun, Lin, Yu-Chang, Lu, Huai-En, Sue, Ming-Wen, Tsou, Nien-Ti, Lo, Yu-Chun, Li, Ssu-Ju, Kuo, Chao-Hung, Chen, You-Yin, Huang, Wei-Chen, Chen, San-Yuan
Format:	Artikel
Sprache:	eng
Schlagworte:	4D hydrogel Biomimetic corrugation Biomolecules distribution Electromicrofluidic platform Spinal cord injury repair
Online-Zugang:	Volltext
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