Carnosine improves aging‐induced cognitive impairment and brain regional neurodegeneration in relation to the neuropathological alterations in the secondary structure of amyloid beta (Aβ)

Aging‐induced proteinopathies, including deterioration of amyloid beta (Aβ) conformation, are associated with reductions in endogenous levels of carnosine and cognitive impairments. Carnosine is a well‐known endogenous antioxidant, which counteracts aging‐induced Aβ plaque formation. The aim of this...

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Veröffentlicht in:Journal of neurochemistry 2021-08, Vol.158 (3), p.710-723
Hauptverfasser: Banerjee, Soumyabrata, Mukherjee, Biswajit, Poddar, Mrinal K., Dunbar, Gary L.
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Sprache:eng
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