Evaluating the psychometric properties of the EQ-5D-5L and SF-6D among patients with haemophilia
Objective The aim of this study was to evaluate the psychometric properties of the EQ-5D-5L and SF-6D, and to compare their performance among patients living with haemophilia in China. Methods A total of 875 Chinese patients completed the EQ-5D-5L, SF-6D, and Haem-A-QoL questionnaires. Construct val...
Gespeichert in:
| Veröffentlicht in: | The European journal of health economics 2021-06, Vol.22 (4), p.547-557 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 557 |
|---|---|
| container_issue | 4 |
| container_start_page | 547 |
| container_title | The European journal of health economics |
| container_volume | 22 |
| creator | Xu, Richard Huan Dong, Dong Luo, Nan Wong, Eliza Lai-Yi Wu, Yushan Yu, Siyue Yang, Renchi Liu, Junshuai Yuan, Huiqin Zhang, Shuyang |
| description | Objective The aim of this study was to evaluate the psychometric properties of the EQ-5D-5L and SF-6D, and to compare their performance among patients living with haemophilia in China. Methods A total of 875 Chinese patients completed the EQ-5D-5L, SF-6D, and Haem-A-QoL questionnaires. Construct validity of the EQ-5D-5L and SF-6D dimensions and indices was assessed by testing hypotheses relating these measures to Haem-A-QoL and clinical measures. The Spearman correlation coefficient was used to assess convergent validity, and oneway analysis of variance (F statistic) was used to assess the known-groups validity (discriminatory power). The agreement between EQ-5D-5L and SF-6D indices was assessed using the intraclass correlation coefficient (ICC) and the Bland-Altman plot. Results Both the EQ-5D-5L and SF-6D indices showed acceptable ceiling and floor effects. As hypothesised, both EQ-5D-5L and SF-6D were significantly correlated with Haem-A-QoL (both dimensions and overall score). EQ-5D-5L and SF-6D indices as well as EQ-VAS differentiated patients are known to differ in severity of haemophilia, bleeding status, disabling levels, and comorbidity. The F statistics in the known-groups comparisons suggested that the EQ-5D-5L was slightly more discriminative than the SF-6D. ICC (0.41) and Bland-Altman plot confirmed that the agreement between the EQ-5D-5L and SF-6D indices was poor. Conclusion Both EQ-5D-5L and SF-6D showed satisfactory construct validity in the measurement of the HRQoL among patients with haemophilia. However, the two instruments may not be used interchangeably in this patient population due to their poor agreement and differing discriminatory power. |
| doi_str_mv | 10.1007/s10198-021-01273-5 |
| format | Article |
| fullrecord | <record><control><sourceid>jstor_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_2505367699</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><jstor_id>45382005</jstor_id><sourcerecordid>45382005</sourcerecordid><originalsourceid>FETCH-LOGICAL-c495t-4c63697b5e51275a7092ad2b13c4d4beb3d020382d73bd3afde6e3e7a20f73583</originalsourceid><addsrcrecordid>eNp9kE2L1TAUhosozof-ARcSEMFNNMnJR7OUmTujcEFEXde0PZ3m0jY1aUfm3xunM464cJXAed6TN09RvODsLWfMvEuccVtSJjhlXBig6lFxzDUvqdGMP76_K1seFScpHRgTwgh4WhwBGM2ZsMfF9921G1a3-OmKLD2SOd00fRhxib4hcwwzxsVjIqG7He8-U3VO1Z64qSVfLqg-J24MOTvnFTgtifz0S096h2OYez9496x40rkh4fO787T4drH7evaB7j9dfjx7v6eNtGqhstGgrakVqvwV5QyzwrWi5tDIVtZYQ8sEg1K0BuoWXNeiRkDjBOsMqBJOizfb3lz6x4ppqUafGhwGN2FYUyUUU6CNtjajr_5BD2GNU26XKZAllxJEpsRGNTGkFLGr5uhHF28qzqrf_qvNf5X9V7f-K5VDL-9Wr_WI7Z_IvfAMkA3AJkw-Pew0WhirmISMwIakPJyuMD7U--_Lr7fUIS0h_t1VQE5Ild2xrOAXZCGkRw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2534814432</pqid></control><display><type>article</type><title>Evaluating the psychometric properties of the EQ-5D-5L and SF-6D among patients with haemophilia</title><source>SpringerLink Journals - AutoHoldings</source><creator>Xu, Richard Huan ; Dong, Dong ; Luo, Nan ; Wong, Eliza Lai-Yi ; Wu, Yushan ; Yu, Siyue ; Yang, Renchi ; Liu, Junshuai ; Yuan, Huiqin ; Zhang, Shuyang</creator><creatorcontrib>Xu, Richard Huan ; Dong, Dong ; Luo, Nan ; Wong, Eliza Lai-Yi ; Wu, Yushan ; Yu, Siyue ; Yang, Renchi ; Liu, Junshuai ; Yuan, Huiqin ; Zhang, Shuyang</creatorcontrib><description>Objective The aim of this study was to evaluate the psychometric properties of the EQ-5D-5L and SF-6D, and to compare their performance among patients living with haemophilia in China. Methods A total of 875 Chinese patients completed the EQ-5D-5L, SF-6D, and Haem-A-QoL questionnaires. Construct validity of the EQ-5D-5L and SF-6D dimensions and indices was assessed by testing hypotheses relating these measures to Haem-A-QoL and clinical measures. The Spearman correlation coefficient was used to assess convergent validity, and oneway analysis of variance (F statistic) was used to assess the known-groups validity (discriminatory power). The agreement between EQ-5D-5L and SF-6D indices was assessed using the intraclass correlation coefficient (ICC) and the Bland-Altman plot. Results Both the EQ-5D-5L and SF-6D indices showed acceptable ceiling and floor effects. As hypothesised, both EQ-5D-5L and SF-6D were significantly correlated with Haem-A-QoL (both dimensions and overall score). EQ-5D-5L and SF-6D indices as well as EQ-VAS differentiated patients are known to differ in severity of haemophilia, bleeding status, disabling levels, and comorbidity. The F statistics in the known-groups comparisons suggested that the EQ-5D-5L was slightly more discriminative than the SF-6D. ICC (0.41) and Bland-Altman plot confirmed that the agreement between the EQ-5D-5L and SF-6D indices was poor. Conclusion Both EQ-5D-5L and SF-6D showed satisfactory construct validity in the measurement of the HRQoL among patients with haemophilia. However, the two instruments may not be used interchangeably in this patient population due to their poor agreement and differing discriminatory power.</description><identifier>ISSN: 1618-7598</identifier><identifier>EISSN: 1618-7601</identifier><identifier>DOI: 10.1007/s10198-021-01273-5</identifier><identifier>PMID: 33761029</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer</publisher><subject>Correlation coefficient ; Economic Policy ; Health Care Management ; Health Economics ; Hemophilia ; Medicine ; Medicine & Public Health ; Original Paper ; Pharmacoeconomics and Health Outcomes ; Public Finance ; Public Health ; Quantitative psychology ; Validation studies ; Validity ; Variance analysis</subject><ispartof>The European journal of health economics, 2021-06, Vol.22 (4), p.547-557</ispartof><rights>Springer-Verlag GmbH Germany, part of Springer Nature 2021</rights><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021</rights><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c495t-4c63697b5e51275a7092ad2b13c4d4beb3d020382d73bd3afde6e3e7a20f73583</citedby><cites>FETCH-LOGICAL-c495t-4c63697b5e51275a7092ad2b13c4d4beb3d020382d73bd3afde6e3e7a20f73583</cites><orcidid>0000-0001-9784-6472</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10198-021-01273-5$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10198-021-01273-5$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51297</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33761029$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Xu, Richard Huan</creatorcontrib><creatorcontrib>Dong, Dong</creatorcontrib><creatorcontrib>Luo, Nan</creatorcontrib><creatorcontrib>Wong, Eliza Lai-Yi</creatorcontrib><creatorcontrib>Wu, Yushan</creatorcontrib><creatorcontrib>Yu, Siyue</creatorcontrib><creatorcontrib>Yang, Renchi</creatorcontrib><creatorcontrib>Liu, Junshuai</creatorcontrib><creatorcontrib>Yuan, Huiqin</creatorcontrib><creatorcontrib>Zhang, Shuyang</creatorcontrib><title>Evaluating the psychometric properties of the EQ-5D-5L and SF-6D among patients with haemophilia</title><title>The European journal of health economics</title><addtitle>Eur J Health Econ</addtitle><addtitle>Eur J Health Econ</addtitle><description>Objective The aim of this study was to evaluate the psychometric properties of the EQ-5D-5L and SF-6D, and to compare their performance among patients living with haemophilia in China. Methods A total of 875 Chinese patients completed the EQ-5D-5L, SF-6D, and Haem-A-QoL questionnaires. Construct validity of the EQ-5D-5L and SF-6D dimensions and indices was assessed by testing hypotheses relating these measures to Haem-A-QoL and clinical measures. The Spearman correlation coefficient was used to assess convergent validity, and oneway analysis of variance (F statistic) was used to assess the known-groups validity (discriminatory power). The agreement between EQ-5D-5L and SF-6D indices was assessed using the intraclass correlation coefficient (ICC) and the Bland-Altman plot. Results Both the EQ-5D-5L and SF-6D indices showed acceptable ceiling and floor effects. As hypothesised, both EQ-5D-5L and SF-6D were significantly correlated with Haem-A-QoL (both dimensions and overall score). EQ-5D-5L and SF-6D indices as well as EQ-VAS differentiated patients are known to differ in severity of haemophilia, bleeding status, disabling levels, and comorbidity. The F statistics in the known-groups comparisons suggested that the EQ-5D-5L was slightly more discriminative than the SF-6D. ICC (0.41) and Bland-Altman plot confirmed that the agreement between the EQ-5D-5L and SF-6D indices was poor. Conclusion Both EQ-5D-5L and SF-6D showed satisfactory construct validity in the measurement of the HRQoL among patients with haemophilia. However, the two instruments may not be used interchangeably in this patient population due to their poor agreement and differing discriminatory power.</description><subject>Correlation coefficient</subject><subject>Economic Policy</subject><subject>Health Care Management</subject><subject>Health Economics</subject><subject>Hemophilia</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Original Paper</subject><subject>Pharmacoeconomics and Health Outcomes</subject><subject>Public Finance</subject><subject>Public Health</subject><subject>Quantitative psychology</subject><subject>Validation studies</subject><subject>Validity</subject><subject>Variance analysis</subject><issn>1618-7598</issn><issn>1618-7601</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNp9kE2L1TAUhosozof-ARcSEMFNNMnJR7OUmTujcEFEXde0PZ3m0jY1aUfm3xunM464cJXAed6TN09RvODsLWfMvEuccVtSJjhlXBig6lFxzDUvqdGMP76_K1seFScpHRgTwgh4WhwBGM2ZsMfF9921G1a3-OmKLD2SOd00fRhxib4hcwwzxsVjIqG7He8-U3VO1Z64qSVfLqg-J24MOTvnFTgtifz0S096h2OYez9496x40rkh4fO787T4drH7evaB7j9dfjx7v6eNtGqhstGgrakVqvwV5QyzwrWi5tDIVtZYQ8sEg1K0BuoWXNeiRkDjBOsMqBJOizfb3lz6x4ppqUafGhwGN2FYUyUUU6CNtjajr_5BD2GNU26XKZAllxJEpsRGNTGkFLGr5uhHF28qzqrf_qvNf5X9V7f-K5VDL-9Wr_WI7Z_IvfAMkA3AJkw-Pew0WhirmISMwIakPJyuMD7U--_Lr7fUIS0h_t1VQE5Ild2xrOAXZCGkRw</recordid><startdate>20210601</startdate><enddate>20210601</enddate><creator>Xu, Richard Huan</creator><creator>Dong, Dong</creator><creator>Luo, Nan</creator><creator>Wong, Eliza Lai-Yi</creator><creator>Wu, Yushan</creator><creator>Yu, Siyue</creator><creator>Yang, Renchi</creator><creator>Liu, Junshuai</creator><creator>Yuan, Huiqin</creator><creator>Zhang, Shuyang</creator><general>Springer</general><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>OQ6</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7WY</scope><scope>7WZ</scope><scope>7X7</scope><scope>7XB</scope><scope>87Z</scope><scope>88C</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8FL</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BEZIV</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FRNLG</scope><scope>FYUFA</scope><scope>F~G</scope><scope>GHDGH</scope><scope>K60</scope><scope>K6~</scope><scope>K9.</scope><scope>L.-</scope><scope>M0C</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>PQBIZ</scope><scope>PQBZA</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PYYUZ</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-9784-6472</orcidid></search><sort><creationdate>20210601</creationdate><title>Evaluating the psychometric properties of the EQ-5D-5L and SF-6D among patients with haemophilia</title><author>Xu, Richard Huan ; Dong, Dong ; Luo, Nan ; Wong, Eliza Lai-Yi ; Wu, Yushan ; Yu, Siyue ; Yang, Renchi ; Liu, Junshuai ; Yuan, Huiqin ; Zhang, Shuyang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c495t-4c63697b5e51275a7092ad2b13c4d4beb3d020382d73bd3afde6e3e7a20f73583</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Correlation coefficient</topic><topic>Economic Policy</topic><topic>Health Care Management</topic><topic>Health Economics</topic><topic>Hemophilia</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Original Paper</topic><topic>Pharmacoeconomics and Health Outcomes</topic><topic>Public Finance</topic><topic>Public Health</topic><topic>Quantitative psychology</topic><topic>Validation studies</topic><topic>Validity</topic><topic>Variance analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Xu, Richard Huan</creatorcontrib><creatorcontrib>Dong, Dong</creatorcontrib><creatorcontrib>Luo, Nan</creatorcontrib><creatorcontrib>Wong, Eliza Lai-Yi</creatorcontrib><creatorcontrib>Wu, Yushan</creatorcontrib><creatorcontrib>Yu, Siyue</creatorcontrib><creatorcontrib>Yang, Renchi</creatorcontrib><creatorcontrib>Liu, Junshuai</creatorcontrib><creatorcontrib>Yuan, Huiqin</creatorcontrib><creatorcontrib>Zhang, Shuyang</creatorcontrib><collection>ECONIS</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ABI/INFORM Collection</collection><collection>ABI/INFORM Global (PDF only)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ABI/INFORM Global (Alumni Edition)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ABI/INFORM Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>Business Premium Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Business Premium Collection (Alumni)</collection><collection>Health Research Premium Collection</collection><collection>ABI/INFORM Global (Corporate)</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Business Collection (Alumni Edition)</collection><collection>ProQuest Business Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ABI/INFORM Professional Advanced</collection><collection>ABI/INFORM Global</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>ProQuest One Business</collection><collection>ProQuest One Business (Alumni)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ABI/INFORM Collection China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>The European journal of health economics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Xu, Richard Huan</au><au>Dong, Dong</au><au>Luo, Nan</au><au>Wong, Eliza Lai-Yi</au><au>Wu, Yushan</au><au>Yu, Siyue</au><au>Yang, Renchi</au><au>Liu, Junshuai</au><au>Yuan, Huiqin</au><au>Zhang, Shuyang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluating the psychometric properties of the EQ-5D-5L and SF-6D among patients with haemophilia</atitle><jtitle>The European journal of health economics</jtitle><stitle>Eur J Health Econ</stitle><addtitle>Eur J Health Econ</addtitle><date>2021-06-01</date><risdate>2021</risdate><volume>22</volume><issue>4</issue><spage>547</spage><epage>557</epage><pages>547-557</pages><issn>1618-7598</issn><eissn>1618-7601</eissn><abstract>Objective The aim of this study was to evaluate the psychometric properties of the EQ-5D-5L and SF-6D, and to compare their performance among patients living with haemophilia in China. Methods A total of 875 Chinese patients completed the EQ-5D-5L, SF-6D, and Haem-A-QoL questionnaires. Construct validity of the EQ-5D-5L and SF-6D dimensions and indices was assessed by testing hypotheses relating these measures to Haem-A-QoL and clinical measures. The Spearman correlation coefficient was used to assess convergent validity, and oneway analysis of variance (F statistic) was used to assess the known-groups validity (discriminatory power). The agreement between EQ-5D-5L and SF-6D indices was assessed using the intraclass correlation coefficient (ICC) and the Bland-Altman plot. Results Both the EQ-5D-5L and SF-6D indices showed acceptable ceiling and floor effects. As hypothesised, both EQ-5D-5L and SF-6D were significantly correlated with Haem-A-QoL (both dimensions and overall score). EQ-5D-5L and SF-6D indices as well as EQ-VAS differentiated patients are known to differ in severity of haemophilia, bleeding status, disabling levels, and comorbidity. The F statistics in the known-groups comparisons suggested that the EQ-5D-5L was slightly more discriminative than the SF-6D. ICC (0.41) and Bland-Altman plot confirmed that the agreement between the EQ-5D-5L and SF-6D indices was poor. Conclusion Both EQ-5D-5L and SF-6D showed satisfactory construct validity in the measurement of the HRQoL among patients with haemophilia. However, the two instruments may not be used interchangeably in this patient population due to their poor agreement and differing discriminatory power.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer</pub><pmid>33761029</pmid><doi>10.1007/s10198-021-01273-5</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0001-9784-6472</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1618-7598 |
| ispartof | The European journal of health economics, 2021-06, Vol.22 (4), p.547-557 |
| issn | 1618-7598 1618-7601 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2505367699 |
| source | SpringerLink Journals - AutoHoldings |
| subjects | Correlation coefficient Economic Policy Health Care Management Health Economics Hemophilia Medicine Medicine & Public Health Original Paper Pharmacoeconomics and Health Outcomes Public Finance Public Health Quantitative psychology Validation studies Validity Variance analysis |
| title | Evaluating the psychometric properties of the EQ-5D-5L and SF-6D among patients with haemophilia |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-28T04%3A12%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-jstor_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Evaluating%20the%20psychometric%20properties%20of%20the%20EQ-5D-5L%20and%20SF-6D%20among%20patients%20with%20haemophilia&rft.jtitle=The%20European%20journal%20of%20health%20economics&rft.au=Xu,%20Richard%20Huan&rft.date=2021-06-01&rft.volume=22&rft.issue=4&rft.spage=547&rft.epage=557&rft.pages=547-557&rft.issn=1618-7598&rft.eissn=1618-7601&rft_id=info:doi/10.1007/s10198-021-01273-5&rft_dat=%3Cjstor_proqu%3E45382005%3C/jstor_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2534814432&rft_id=info:pmid/33761029&rft_jstor_id=45382005&rfr_iscdi=true |