CircPITX1 Regulates Proliferation, Angiogenesis, Migration, Invasion, and Cell Cycle of Human Glioblastoma Cells by Targeting miR-584-5p/KPNB1 Axis

Recent researches reported that several circular RNAs (circRNAs) were associated with the glioblastoma (GBM) progression, while the regulatory role of circPITX1 remains unknown in GBM. The real-time quantitative polymerase chain reaction (RT-qPCR) was used to quantify circPITX1, miR-584-5p, and kary...

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Veröffentlicht in:	Journal of molecular neuroscience 2021-08, Vol.71 (8), p.1683-1695
Hauptverfasser:	Cao, Yiqiang, Wang, Fei, Chen, Yu, Wang, Yonggang, Song, Hai, Long, Jiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Animals Assaying beta Karyopherins - genetics beta Karyopherins - metabolism Biomedical and Life Sciences Biomedicine Brain cancer Brain Neoplasms - genetics Brain Neoplasms - metabolism Brain Neoplasms - pathology Cell Biology Cell Cycle Cell Line Cell Line, Tumor Cell migration Cell Movement Cell Proliferation Cholecystokinin Chromosome 5 Flow cytometry Glioblastoma Glioblastoma - genetics Glioblastoma - metabolism Glioblastoma - pathology Glioblastoma cells Humans Kinases Mice Mice, Nude MicroRNAs - genetics MicroRNAs - metabolism Neovascularization, Pathologic - genetics Neovascularization, Pathologic - metabolism Neovascularization, Pathologic - pathology Neurochemistry Neurology Neurosciences Paired Box Transcription Factors - genetics Polymerase chain reaction Proteomics RNA, Circular - genetics RNA, Circular - metabolism Tissues Xenografts Xenotransplantation
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