The evolutionary trade‐offs in phage‐resistant Klebsiella pneumoniae entail cross‐phage sensitization and loss of multidrug resistance

Summary Bacteriophage therapy is currently being evaluated as a critical complement to traditional antibiotic treatment. However, the emergence of phage resistance is perceived as a major hurdle to the sustainable implementation of this antimicrobial strategy. By combining comprehensive genomics and...

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Veröffentlicht in:Environmental microbiology 2021-12, Vol.23 (12), p.7723-7740
Hauptverfasser: Majkowska‐Skrobek, Grazyna, Markwitz, Pawel, Sosnowska, Ewelina, Lood, Cédric, Lavigne, Rob, Drulis‐Kawa, Zuzanna
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Sprache:eng
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