RB1 gene mutations are a distinct predictive factor in Merkel cell carcinoma

Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine carcinoma that tends to show local recurrence and metastasis. Typically, MCC is polyomavirus (MCPyV)‐associated and cytokeratin 20 (CK20) positive. However, little is known about this tumor and its origins. Here, we aimed to determine th...

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Veröffentlicht in:	Pathology international 2021-05, Vol.71 (5), p.337-347
Hauptverfasser:	Muto, Yusuke, Ryo, Eijitsu, Namikawa, Kenjiro, Takahashi, Akira, Ogata, Dai, Fujimura, Taku, Yatabe, Yasushi, Aiba, Setsuya, Yamazaki, Naoya, Mori, Taisuke
Format:	Artikel
Sprache:	eng
Schlagworte:	clinicopathological examination Cytokeratin Gene sequencing Immunohistochemistry Lymph nodes Merkel cell carcinoma Metastases Metastasis Mutation Neuroendocrine tumors Origins RB1 Retinoblastoma protein
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