Impact of SDH Mutations in Alternaria solani on Recently Developed SDHI Fungicides Adepidyn and Solatenol
Early blight, caused by , is observed annually in all midwestern potato production areas. The use of foliar fungicides remains a primary management strategy. However, has developed reduced sensitivity or resistance to many single-site fungicides such as quinone outside inhibitor (QoI, FRAC group 11)...
Gespeichert in:
| Veröffentlicht in: | Plant disease 2021-10, Vol.105 (10), p.3015-3024 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 3024 |
|---|---|
| container_issue | 10 |
| container_start_page | 3015 |
| container_title | Plant disease |
| container_volume | 105 |
| creator | Budde-Rodriguez, Sarah Celoy, Rhodesia M Mallik, Ipsita Pasche, Julie S Gudmestad, Neil C |
| description | Early blight, caused by
, is observed annually in all midwestern potato production areas. The use of foliar fungicides remains a primary management strategy. However,
has developed reduced sensitivity or resistance to many single-site fungicides such as quinone outside inhibitor (QoI, FRAC group 11), succinate dehydrogenase inhibitor (SDHI, FRAC group 7), demethylation inhibitor (DMI, FRAC group 3), and anilinopyrimidine (AP, FRAC group 9) fungicides. Boscalid, fluopyram, solatenol, and adepidyn are EPA-registered SDHI fungicides used commercially on a variety of crops, including potato. Five SDH mutations have been characterized previously in
that affect the efficacy of boscalid while only one of these mutations has been demonstrated to negatively affect fluopyram efficacy. Conidial germination assays were used to determine if a shift in sensitivity has occurred in these SDHI fungicides.
isolates collected prior to the commercial application of SDHI fungicides (baseline) were compared with recently collected isolates (nonbaseline). Greenhouse evaluations were conducted also to evaluate the efficacy of boscalid, fluopyram, solatenol, and adepidyn on
isolates possessing individual SDH mutations. Additionally, field trials were conducted to determine the effects of application of these SDHI fungicides on the frequency of SDH mutations. Fluopyram, solatenol, and adepidyn had high intrinsic activity against
when compared with boscalid, based on in vitro assays. The application of adepidyn and solatenol resulted in greater early blight control than the application of boscalid and fluopyram in greenhouse experiments. Molecular characterization of
isolates collected from the field trials determined that the frequency of the H134R-mutation can increase in response to more recently developed SDHI fungicides. In contrast, the H278R/Y- and H133R-mutations decreased to the point of being nearly absent in these field experiments. |
| doi_str_mv | 10.1094/PDIS-12-20-2718-RE |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2503438586</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2503438586</sourcerecordid><originalsourceid>FETCH-LOGICAL-c347t-ef2aa71c666eac6eef22af3ffbb331ee5a937815cb7c9db1b4e69c78834ac4953</originalsourceid><addsrcrecordid>eNo9kMtKxDAUhoMoOl5ewIVk6SaaW5NmOTijDijKqOuQpqcS6SS1aYV5ezt4WR0O5_9-OB9C54xeMWrk9fNi9UIYJ5wSrllJ1ss9NGNGCqKV4ftoRplhhBumj9Bxzh-UUilVeYiOhNBCSU1nKKw2nfMDTg1-Wdzjx3FwQ0gx4xDxvB2gj64PDufUuhhwingNHuLQbvECvqBNHdQ7cIVvx_gefKgh43kNXai3Ebs4HSdygJjaU3TQuDbD2e88QW-3y9ebe_LwdLe6mT8QL6QeCDTcOc28UgqcVzDt3DWiaapKCAZQOCN0yQpfaW_qilUSlPG6LIV0XppCnKDLn96uT58j5MFuQvbQTg9AGrPlBRVSlEWppij_ifo-5dxDY7s-bFy_tYzanWK7U2wZt5zanWK7Xk7QxW__WG2g_kf-nIpvIt14rg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2503438586</pqid></control><display><type>article</type><title>Impact of SDH Mutations in Alternaria solani on Recently Developed SDHI Fungicides Adepidyn and Solatenol</title><source>MEDLINE</source><source>American Phytopathological Society</source><source>Alma/SFX Local Collection</source><source>EZB Electronic Journals Library</source><creator>Budde-Rodriguez, Sarah ; Celoy, Rhodesia M ; Mallik, Ipsita ; Pasche, Julie S ; Gudmestad, Neil C</creator><creatorcontrib>Budde-Rodriguez, Sarah ; Celoy, Rhodesia M ; Mallik, Ipsita ; Pasche, Julie S ; Gudmestad, Neil C</creatorcontrib><description>Early blight, caused by
, is observed annually in all midwestern potato production areas. The use of foliar fungicides remains a primary management strategy. However,
has developed reduced sensitivity or resistance to many single-site fungicides such as quinone outside inhibitor (QoI, FRAC group 11), succinate dehydrogenase inhibitor (SDHI, FRAC group 7), demethylation inhibitor (DMI, FRAC group 3), and anilinopyrimidine (AP, FRAC group 9) fungicides. Boscalid, fluopyram, solatenol, and adepidyn are EPA-registered SDHI fungicides used commercially on a variety of crops, including potato. Five SDH mutations have been characterized previously in
that affect the efficacy of boscalid while only one of these mutations has been demonstrated to negatively affect fluopyram efficacy. Conidial germination assays were used to determine if a shift in sensitivity has occurred in these SDHI fungicides.
isolates collected prior to the commercial application of SDHI fungicides (baseline) were compared with recently collected isolates (nonbaseline). Greenhouse evaluations were conducted also to evaluate the efficacy of boscalid, fluopyram, solatenol, and adepidyn on
isolates possessing individual SDH mutations. Additionally, field trials were conducted to determine the effects of application of these SDHI fungicides on the frequency of SDH mutations. Fluopyram, solatenol, and adepidyn had high intrinsic activity against
when compared with boscalid, based on in vitro assays. The application of adepidyn and solatenol resulted in greater early blight control than the application of boscalid and fluopyram in greenhouse experiments. Molecular characterization of
isolates collected from the field trials determined that the frequency of the H134R-mutation can increase in response to more recently developed SDHI fungicides. In contrast, the H278R/Y- and H133R-mutations decreased to the point of being nearly absent in these field experiments.</description><identifier>ISSN: 0191-2917</identifier><identifier>EISSN: 1943-7692</identifier><identifier>DOI: 10.1094/PDIS-12-20-2718-RE</identifier><identifier>PMID: 33736470</identifier><language>eng</language><publisher>United States</publisher><subject>Alternaria ; Drug Resistance, Fungal - genetics ; Fungicides, Industrial - pharmacology ; Mutation ; Norbornanes ; Plant Diseases ; Pyrazoles ; Succinate Dehydrogenase - genetics</subject><ispartof>Plant disease, 2021-10, Vol.105 (10), p.3015-3024</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c347t-ef2aa71c666eac6eef22af3ffbb331ee5a937815cb7c9db1b4e69c78834ac4953</citedby><cites>FETCH-LOGICAL-c347t-ef2aa71c666eac6eef22af3ffbb331ee5a937815cb7c9db1b4e69c78834ac4953</cites><orcidid>0000-0002-2787-4635 ; 0000-0001-5660-9796</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,3724,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33736470$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Budde-Rodriguez, Sarah</creatorcontrib><creatorcontrib>Celoy, Rhodesia M</creatorcontrib><creatorcontrib>Mallik, Ipsita</creatorcontrib><creatorcontrib>Pasche, Julie S</creatorcontrib><creatorcontrib>Gudmestad, Neil C</creatorcontrib><title>Impact of SDH Mutations in Alternaria solani on Recently Developed SDHI Fungicides Adepidyn and Solatenol</title><title>Plant disease</title><addtitle>Plant Dis</addtitle><description>Early blight, caused by
, is observed annually in all midwestern potato production areas. The use of foliar fungicides remains a primary management strategy. However,
has developed reduced sensitivity or resistance to many single-site fungicides such as quinone outside inhibitor (QoI, FRAC group 11), succinate dehydrogenase inhibitor (SDHI, FRAC group 7), demethylation inhibitor (DMI, FRAC group 3), and anilinopyrimidine (AP, FRAC group 9) fungicides. Boscalid, fluopyram, solatenol, and adepidyn are EPA-registered SDHI fungicides used commercially on a variety of crops, including potato. Five SDH mutations have been characterized previously in
that affect the efficacy of boscalid while only one of these mutations has been demonstrated to negatively affect fluopyram efficacy. Conidial germination assays were used to determine if a shift in sensitivity has occurred in these SDHI fungicides.
isolates collected prior to the commercial application of SDHI fungicides (baseline) were compared with recently collected isolates (nonbaseline). Greenhouse evaluations were conducted also to evaluate the efficacy of boscalid, fluopyram, solatenol, and adepidyn on
isolates possessing individual SDH mutations. Additionally, field trials were conducted to determine the effects of application of these SDHI fungicides on the frequency of SDH mutations. Fluopyram, solatenol, and adepidyn had high intrinsic activity against
when compared with boscalid, based on in vitro assays. The application of adepidyn and solatenol resulted in greater early blight control than the application of boscalid and fluopyram in greenhouse experiments. Molecular characterization of
isolates collected from the field trials determined that the frequency of the H134R-mutation can increase in response to more recently developed SDHI fungicides. In contrast, the H278R/Y- and H133R-mutations decreased to the point of being nearly absent in these field experiments.</description><subject>Alternaria</subject><subject>Drug Resistance, Fungal - genetics</subject><subject>Fungicides, Industrial - pharmacology</subject><subject>Mutation</subject><subject>Norbornanes</subject><subject>Plant Diseases</subject><subject>Pyrazoles</subject><subject>Succinate Dehydrogenase - genetics</subject><issn>0191-2917</issn><issn>1943-7692</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kMtKxDAUhoMoOl5ewIVk6SaaW5NmOTijDijKqOuQpqcS6SS1aYV5ezt4WR0O5_9-OB9C54xeMWrk9fNi9UIYJ5wSrllJ1ss9NGNGCqKV4ftoRplhhBumj9Bxzh-UUilVeYiOhNBCSU1nKKw2nfMDTg1-Wdzjx3FwQ0gx4xDxvB2gj64PDufUuhhwingNHuLQbvECvqBNHdQ7cIVvx_gefKgh43kNXai3Ebs4HSdygJjaU3TQuDbD2e88QW-3y9ebe_LwdLe6mT8QL6QeCDTcOc28UgqcVzDt3DWiaapKCAZQOCN0yQpfaW_qilUSlPG6LIV0XppCnKDLn96uT58j5MFuQvbQTg9AGrPlBRVSlEWppij_ifo-5dxDY7s-bFy_tYzanWK7U2wZt5zanWK7Xk7QxW__WG2g_kf-nIpvIt14rg</recordid><startdate>202110</startdate><enddate>202110</enddate><creator>Budde-Rodriguez, Sarah</creator><creator>Celoy, Rhodesia M</creator><creator>Mallik, Ipsita</creator><creator>Pasche, Julie S</creator><creator>Gudmestad, Neil C</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-2787-4635</orcidid><orcidid>https://orcid.org/0000-0001-5660-9796</orcidid></search><sort><creationdate>202110</creationdate><title>Impact of SDH Mutations in Alternaria solani on Recently Developed SDHI Fungicides Adepidyn and Solatenol</title><author>Budde-Rodriguez, Sarah ; Celoy, Rhodesia M ; Mallik, Ipsita ; Pasche, Julie S ; Gudmestad, Neil C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c347t-ef2aa71c666eac6eef22af3ffbb331ee5a937815cb7c9db1b4e69c78834ac4953</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Alternaria</topic><topic>Drug Resistance, Fungal - genetics</topic><topic>Fungicides, Industrial - pharmacology</topic><topic>Mutation</topic><topic>Norbornanes</topic><topic>Plant Diseases</topic><topic>Pyrazoles</topic><topic>Succinate Dehydrogenase - genetics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Budde-Rodriguez, Sarah</creatorcontrib><creatorcontrib>Celoy, Rhodesia M</creatorcontrib><creatorcontrib>Mallik, Ipsita</creatorcontrib><creatorcontrib>Pasche, Julie S</creatorcontrib><creatorcontrib>Gudmestad, Neil C</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Plant disease</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Budde-Rodriguez, Sarah</au><au>Celoy, Rhodesia M</au><au>Mallik, Ipsita</au><au>Pasche, Julie S</au><au>Gudmestad, Neil C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Impact of SDH Mutations in Alternaria solani on Recently Developed SDHI Fungicides Adepidyn and Solatenol</atitle><jtitle>Plant disease</jtitle><addtitle>Plant Dis</addtitle><date>2021-10</date><risdate>2021</risdate><volume>105</volume><issue>10</issue><spage>3015</spage><epage>3024</epage><pages>3015-3024</pages><issn>0191-2917</issn><eissn>1943-7692</eissn><abstract>Early blight, caused by
, is observed annually in all midwestern potato production areas. The use of foliar fungicides remains a primary management strategy. However,
has developed reduced sensitivity or resistance to many single-site fungicides such as quinone outside inhibitor (QoI, FRAC group 11), succinate dehydrogenase inhibitor (SDHI, FRAC group 7), demethylation inhibitor (DMI, FRAC group 3), and anilinopyrimidine (AP, FRAC group 9) fungicides. Boscalid, fluopyram, solatenol, and adepidyn are EPA-registered SDHI fungicides used commercially on a variety of crops, including potato. Five SDH mutations have been characterized previously in
that affect the efficacy of boscalid while only one of these mutations has been demonstrated to negatively affect fluopyram efficacy. Conidial germination assays were used to determine if a shift in sensitivity has occurred in these SDHI fungicides.
isolates collected prior to the commercial application of SDHI fungicides (baseline) were compared with recently collected isolates (nonbaseline). Greenhouse evaluations were conducted also to evaluate the efficacy of boscalid, fluopyram, solatenol, and adepidyn on
isolates possessing individual SDH mutations. Additionally, field trials were conducted to determine the effects of application of these SDHI fungicides on the frequency of SDH mutations. Fluopyram, solatenol, and adepidyn had high intrinsic activity against
when compared with boscalid, based on in vitro assays. The application of adepidyn and solatenol resulted in greater early blight control than the application of boscalid and fluopyram in greenhouse experiments. Molecular characterization of
isolates collected from the field trials determined that the frequency of the H134R-mutation can increase in response to more recently developed SDHI fungicides. In contrast, the H278R/Y- and H133R-mutations decreased to the point of being nearly absent in these field experiments.</abstract><cop>United States</cop><pmid>33736470</pmid><doi>10.1094/PDIS-12-20-2718-RE</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0002-2787-4635</orcidid><orcidid>https://orcid.org/0000-0001-5660-9796</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0191-2917 |
| ispartof | Plant disease, 2021-10, Vol.105 (10), p.3015-3024 |
| issn | 0191-2917 1943-7692 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2503438586 |
| source | MEDLINE; American Phytopathological Society; Alma/SFX Local Collection; EZB Electronic Journals Library |
| subjects | Alternaria Drug Resistance, Fungal - genetics Fungicides, Industrial - pharmacology Mutation Norbornanes Plant Diseases Pyrazoles Succinate Dehydrogenase - genetics |
| title | Impact of SDH Mutations in Alternaria solani on Recently Developed SDHI Fungicides Adepidyn and Solatenol |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T07%3A51%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Impact%20of%20SDH%20Mutations%20in%20Alternaria%20solani%20on%20Recently%20Developed%20SDHI%20Fungicides%20Adepidyn%20and%20Solatenol&rft.jtitle=Plant%20disease&rft.au=Budde-Rodriguez,%20Sarah&rft.date=2021-10&rft.volume=105&rft.issue=10&rft.spage=3015&rft.epage=3024&rft.pages=3015-3024&rft.issn=0191-2917&rft.eissn=1943-7692&rft_id=info:doi/10.1094/PDIS-12-20-2718-RE&rft_dat=%3Cproquest_cross%3E2503438586%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2503438586&rft_id=info:pmid/33736470&rfr_iscdi=true |