Steroid Sulfation in Adrenal Tumors

The adrenal cortex produces specific steroid hormones including steroid sulfates such as dehydroepiandrosterone sulfate (DHEAS), the most abundant steroid hormone in the human circulation. Steroid sulfation involves a multistep enzyme machinery that may be impaired by inborn errors of steroid metabo...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2021-12, Vol.106 (12), p.3385-3397
Hauptverfasser:	Mueller, Jonathan Wolf, Vogg, Nora, Lightning, Thomas Alec, Weigand, Isabel, Ronchi, Cristina L, Foster, Paul A, Kroiss, Matthias
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Gland Neoplasms - metabolism Adrenal Gland Neoplasms - pathology Adrenocortical Carcinoma - metabolism Adrenocortical Carcinoma - pathology Androgens Animals Dehydroepiandrosterone Enzymes Estrogen Humans Mass spectrometry Physiological aspects Steroids - chemistry Steroids - metabolism Sulfates Sulfates - chemistry Sulfates - metabolism Sulfotransferases - metabolism Tumors
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