Emodin Suppresses the Migration and Invasion of Melanoma Cells

Emodin (1,3,8-trihydroxy-6-methylanthraquinone), as an active ingredient in rhubarb roots and rhizomes, has been reported to possess various pharmacological properties including anti-tumor effects. Recent studies have confirmed that emodin inhibited cell proliferation and induced apoptosis of cancer...

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Veröffentlicht in:	Biological & pharmaceutical bulletin 2021/06/01, Vol.44(6), pp.771-779
Hauptverfasser:	Liu, Chi, Chen, Liang, Wang, Wanchen, Qin, Dengke, Jia, Chuanlong, Yuan, Mingjie, Wang, Heng, Guo, Yu, Zhu, Jingjing, Zhou, Yiqun, Zhao, Haiguang, Liu, Tianyi
Format:	Artikel
Sprache:	eng
Schlagworte:	Annexin V Apoptosis Bax protein Bcl-2 protein Cell growth Cell migration Cell proliferation Cholecystokinin Emodin Fluorescein isothiocyanate Gelatinase A Immunofluorescence invasion Melanoma Metastases Metastasis migration Propidium iodide Protein expression Rhizomes Signal transduction Wnt Wnt protein Wound healing β-Catenin
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