Lateral ventral tegmental area GABAergic and glutamatergic modulation of conditioned learning

The firing activity of dorso-medial-striatal-cholinergic interneurons (dmCINs) is a neural correlate of classical conditioning. Tonically active, they pause in response to salient stimuli, mediating acquisition of predictive cues/outcome associations. Cortical and thalamic inputs are typical of the...

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Veröffentlicht in:	Cell reports (Cambridge) 2021-03, Vol.34 (11), p.108867-108867, Article 108867
Hauptverfasser:	Rizzi, Giorgio, Li, Zhuoliang, Hogrefe, Norbert, Tan, Kelly R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acoustic Stimulation Animals brain clearing Choline - metabolism cholinergic interneurons Conditioning, Classical Cues Discrimination Learning Electroshock Fear fear conditioning Female GABA neurons GABAergic Neurons - physiology glutamate neurons Glutamates - metabolism Interneurons - physiology Learning Male Mice Mice, Inbred C57BL midbrain midbrain in vivo calcium imaging optogenetic inhibition Synapses - physiology Thalamus - physiology Ventral Tegmental Area - physiology Vesicular Glutamate Transport Protein 2 - metabolism
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