In vitro behavior of dronedarone hydrochloride loaded pellets using vacuum impregnation technique

[Display omitted] •Inert and porous pellets were prepared by extrusion/spheronization process.•Drug suspensions were loaded onto the pellets using vacuum impregnation technique.•Type of surfactant used in preparation of drug suspensions affects the drug content.•Drug dissolution was additionally con...

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Veröffentlicht in:	European journal of pharmaceutics and biopharmaceutics 2021-05, Vol.162, p.70-81
Hauptverfasser:	Gretić, M., Štanfel, M., Barbarić, J., Rimac, N., Matijašić, G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biorelevant media Dronedarone hydrochloride In vitro drug release Pellet coating Pellets Vacuum impregnation
Online-Zugang:	Volltext
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