Yes associated protein 1 promotes resistance to 5-fluorouracil in gastric cancer by regulating GLUT3-dependent glycometabolism reprogramming of tumor-associated macrophages

The antimetabolite 5-fluorouracil (5-FU) is a widely used chemotherapy regimen for the treatment of gastric cancer (GC). However, resistance to 5-FU remains a major drawback in the clinical use. The treatments of anti-tumor chemo-agents recruit tumor associated macrophages (TAMs) which are highly im...

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Veröffentlicht in:	Archives of biochemistry and biophysics 2021-05, Vol.702, p.108838-108838, Article 108838
Hauptverfasser:	He, Zhanke, Chen, Da, Wu, Jiani, Sui, Chuyang, Deng, Xiangqian, Zhang, Penghao, Chen, Zechang, Liu, Diankun, Yu, Jiang, Shi, Jiaolong, Li, Guoxin, Yao, Xingxing
Format:	Artikel
Sprache:	eng
Schlagworte:	5-FU Gastric cancer Glycometabolism reprogramming IL13 Tumor associated macrophage YAP1
Online-Zugang:	Volltext
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