Development and Application of Subtype-Selective Fluorescent Antagonists for the Study of the Human Adenosine A1 Receptor in Living Cells

The adenosine A1 receptor (A1AR) is a G-protein-coupled receptor (GPCR) that provides important therapeutic opportunities for a number of conditions including congestive heart failure, tachycardia, and neuropathic pain. The development of A1AR-selective fluorescent ligands will enhance our understan...

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Veröffentlicht in:	Journal of medicinal chemistry 2021-05, Vol.64 (10), p.6670-6695
Hauptverfasser:	Comeo, Eleonora, Trinh, Phuc, Nguyen, Anh T, Nowell, Cameron J, Kindon, Nicholas D, Soave, Mark, Stoddart, Leigh A, White, Jonathan M, Hill, Stephen J, Kellam, Barrie, Halls, Michelle L, May, Lauren T, Scammells, Peter J
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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