The role of inflammatory mediators in epilepsy: Focus on developmental and epileptic encephalopathies and therapeutic implications

•Uncontrolled epileptic activity leads to cognitive, motor and behavior impairment.•Seizures can activate inflammatory pathways that contribute to their persistence.•Innate immunity involvement is evidenced in animal models and epileptic patients.•The treatment of West Syndrome is a paradigm for oth...

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Veröffentlicht in:	Epilepsy research 2021-05, Vol.172, p.106588-106588, Article 106588
Hauptverfasser:	Orsini, Alessandro, Foiadelli, Thomas, Costagliola, Giorgio, Michev, Alexandre, Consolini, Rita, Vinci, Federica, Peroni, Diego, Striano, Pasquale, Savasta, Salvatore
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chemokine Chemokines Cytokine Cytokines Epilepsy Epilepsy - drug therapy Immunomodulating Agents Inflammation Mediators Neuroinflammation Neuroinflammatory Diseases Steroid West syndrome
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