Dimethyl Itaconate‐Loaded Nanofibers Rewrite Macrophage Polarization, Reduce Inflammation, and Enhance Repair of Myocardic Infarction

Cellular metabolism plays a major role in the regulation of inflammation. The inflammatory macrophages undergo a wide‐range of metabolic rewriting due to the production of significant amount of itaconate metabolite from cis‐aconitate in the tricarboxylic acid cycle. This itaconate molecule has been...

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Veröffentlicht in:Small (Weinheim an der Bergstrasse, Germany) Germany), 2021-04, Vol.17 (17), p.e2006992-n/a
Hauptverfasser: Nakkala, Jayachandra Reddy, Yao, Yuejun, Zhai, Zihe, Duan, Yiyuan, Zhang, Deteng, Mao, Zhengwei, Lu, Linrong, Gao, Changyou
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Sprache:eng
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