Angiopep-2-modified calcium arsenite-loaded liposomes for targeted and pH-responsive delivery for anti-glioma therapy

The blood-brain barrier (BBB) is the most critical obstacle in the treatment of central nervous system disorders, such as glioma, the most typical type of brain tumor. To overcome the BBB and enhance drug-penetration abilities, we used angiopep-2-modified liposomes to deliver arsenic trioxide (ATO)...

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Veröffentlicht in:	Biochemical and biophysical research communications 2021-04, Vol.551, p.14-20
Hauptverfasser:	Xu, Hengwu, Li, Chaoqun, Wei, Yinghui, Zheng, Hangsheng, Zheng, Hongyue, Wang, Binhui, Piao, Ji-Gang, Li, Fanzhu
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiopep-2 Arsenic trioxide Blood-brain barrier Calcium arsenite liposome Dual targeting Glioma
Online-Zugang:	Volltext
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