Reductive Alkylation of Quinolines to N‑Alkyl Tetrahydroquinolines Catalyzed by Arylboronic Acid
A boronic acid catalyzed one-pot tandem reduction of quinolines to tetrahydroquinolines followed by reductive alkylation by the aldehyde has been demonstrated. This step-economcial synthesis of N-alkyl tetrahydroquinolines has been achieved directly from readily available quinolines, aldehydes, and...
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Veröffentlicht in: | Organic letters 2021-04, Vol.23 (7), p.2437-2442 |
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Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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