Reductive Alkylation of Quinolines to N‑Alkyl Tetrahydroquinolines Catalyzed by Arylboronic Acid

A boronic acid catalyzed one-pot tandem reduction of quinolines to tetrahydroquinolines followed by reductive alkylation by the aldehyde has been demonstrated. This step-economcial synthesis of N-alkyl tetrahydroquinolines has been achieved directly from readily available quinolines, aldehydes, and...

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Veröffentlicht in:Organic letters 2021-04, Vol.23 (7), p.2437-2442
Hauptverfasser: Adhikari, Priyanka, Bhattacharyya, Dipanjan, Nandi, Sekhar, Kancharla, Pavan K, Das, Animesh
Format: Artikel
Sprache:eng
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