TMKS8A, an antibacterial and cytotoxic chlorinated α-lapachone, from a sea slug-derived actinomycete of the genus Streptomyces

TMKS8A ( 1 ), a new chlorinated α-lapachone derivative, along with five known related metabolites, A80915 C ( 2 ), SF2415B1 ( 3 ), chlorinated dihydroquinone 3 ( 4 ), SF2415B3 ( 5 ), and A80915 C ( 6 ), were identified from the culture extract of Streptomyces sp. TMKS8, which was isolated from a sea...

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Veröffentlicht in:Journal of antibiotics 2021-07, Vol.74 (7), p.464-469
Hauptverfasser: Zhang, Zhiwei, Sibero, Mada Triandala, Kai, Akiho, Fukaya, Keisuke, Urabe, Daisuke, Igarashi, Yasuhiro
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Sprache:eng
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