Linking 7-Nitrobenzo-2-oxa-1,3-diazole (NBD) to Triphenylphosphonium Yields Mitochondria-Targeted Protonophore and Antibacterial Agent

Appending lipophilic cations to small molecules has been widely used to produce mitochondria-targeted compounds with specific activities. In this work, we obtained a series of derivatives of the well-known fluorescent dye 7-nitrobenzo-2-oxa-1,3-diazole (NBD). According to the previous data [Denisov...

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Veröffentlicht in:Biochemistry (Moscow) 2020-12, Vol.85 (12-13), p.1578-1590
Hauptverfasser: Iaubasarova, I. R., Khailova, L. S., Nazarov, P. A., Rokitskaya, T. I., Silachev, D. N., Danilina, T. I., Plotnikov, E. Y., Denisov, S. S., Kirsanov, R. S., Korshunova, G. A., Kotova, E. A., Zorov, D. B., Antonenko, Y. N.
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Sprache:eng
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