Ketone therapy for heart failure: current evidence for clinical use

Abstract During conditions that result in depleted circulating glucose levels, ketone bodies synthesized in the liver are necessary fuel substrates for the brain. In other organs, such as the heart, the reliance on ketones for generating energy in the absence of glucose is less important as the hear...

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Veröffentlicht in:	Cardiovascular research 2022-03, Vol.118 (4), p.977-987
Hauptverfasser:	Takahara, Shingo, Soni, Shubham, Maayah, Zaid H, Ferdaoussi, Mourad, Dyck, Jason R B
Format:	Artikel
Sprache:	eng
Schlagworte:	Fatty Acids - metabolism Glucose - metabolism Heart Failure - diagnosis Heart Failure - drug therapy Humans Ketone Bodies - metabolism Ketones - therapeutic use
Online-Zugang:	Volltext
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