Application of a dissolved oxygen control strategy to increase the expression of Streptococcus suis glutamate dehydrogenase in Escherichia coli

The accumulation of acetate in Escherichia coli inhibits cell growth and desired protein synthesis, and cell density and protein expression are increased by reduction of acetate excretion. Dissolved oxygen (DO) is an important parameter for acetate synthesis, and the accumulation of acetate is inver...

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Veröffentlicht in:	World journal of microbiology & biotechnology 2021-04, Vol.37 (4), p.60-60, Article 60
Hauptverfasser:	Cheng, Likun, Zhao, Chunguang, Yang, Xiuyan, Song, Zheng, Lin, Chuwen, Zhao, Xiubao, Wang, Jinliang, Wang, Jing, Wang, Lei, Xia, Xiaojing, Shen, Zhiqiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Accumulation Acetic acid Anaplerotic pathways Applied Microbiology Biochemistry Biomedical and Life Sciences Biotechnology Cell density Dehydrogenase Dehydrogenases Density Dissolved oxygen E coli Environmental Engineering/Biotechnology Escherichia coli Fluctuations Flux Glutamate dehydrogenase Life Sciences Microbiology Original Paper Protein biosynthesis Protein expression Protein synthesis Proteins Streptococcus Streptococcus infections Transcription Tricarboxylic acid cycle
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