A mucinous cystic neoplasm of the pancreas containing an undifferentiated carcinoma component and harboring the NRAS driver mutation
A woman in her 20s visited our hospital with a chief complaint of abdominal distension and back pain. She was diagnosed with a cystic tumor (diameter 16 cm) in the tail of the pancreas and underwent a combined distal pancreatectomy, splenectomy, and left adrenalectomy. Histopathologically, the tumor...
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| Veröffentlicht in: | Clinical journal of gastroenterology 2021-06, Vol.14 (3), p.910-917 |
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| container_title | Clinical journal of gastroenterology |
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| creator | Hisanaga, Etsuko Sano, Takaaki Yoshida, Yuka Ishii, Norihiro Shirabe, Ken Ikota, Hayato |
| description | A woman in her 20s visited our hospital with a chief complaint of abdominal distension and back pain. She was diagnosed with a cystic tumor (diameter 16 cm) in the tail of the pancreas and underwent a combined distal pancreatectomy, splenectomy, and left adrenalectomy. Histopathologically, the tumor presented as a mucinous cystic neoplasm with an undifferentiated carcinoma component of the pancreas. In addition, the cells demonstrated a partial rhabdoid-like morphology. These findings were considered relatively typical for a mucinous cystic neoplasm in the tail of the pancreas in a young woman. However,
NRAS
mutation, which is rare in pancreatic tumors, was detected. |
| doi_str_mv | 10.1007/s12328-021-01380-z |
| format | Article |
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NRAS
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NRAS
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NRAS
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| ispartof | Clinical journal of gastroenterology, 2021-06, Vol.14 (3), p.910-917 |
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| language | eng |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Abdominal Surgery Carcinoma Case Report Colorectal Surgery Female Gastroenterology GTP Phosphohydrolases Hepatology Humans Medicine Medicine & Public Health Membrane Proteins - genetics Mutation Pancreas Pancreatectomy Pancreatic Neoplasms - genetics Pancreatic Neoplasms - surgery Surgical Oncology |
| title | A mucinous cystic neoplasm of the pancreas containing an undifferentiated carcinoma component and harboring the NRAS driver mutation |
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