Zp4 is completely dispensable for fertility in female rats

Zona pellucida (ZP), which is composed of at most four extracellular glycoproteins (ZP1, ZP2, ZP3, and ZP4) in mammals, shelters the oocytes and is vital in female fertility. Several studies have identified the indispensable roles of ZP1–3 in maintaining normal female fertility. However, the underst...

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Veröffentlicht in:	Biology of reproduction 2021-06, Vol.104 (6), p.1282-1291
Hauptverfasser:	Zeng, Ming-Hua, Wang, Yan, Huang, Hua-Lin, Quan, Ru-Ping, Yang, Jun-Ting, Guo, Dan, Sun, Ying, Lv, Chao, Li, Tian-Ying, Wang, Le, Tan, Hang-Jin, Long, Pan-Pan, Deng, Hong-Wen, Xiao, Hong-Mei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CRISPR Female Fertility Fertility - genetics Fertilization Gene Editing Glycoproteins In vitro fertilization Infertility knockout Mammals Morphology oocyte development Oocytes Oogenesis Ovulation rat Rats - genetics Rats - physiology RESEARCH ARTICLE Scientific equipment and supplies industry Zona pellucida Zona Pellucida Glycoproteins - genetics Zona Pellucida Glycoproteins - metabolism
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