Specific proteome changes in platelets from individuals with GATA1-, GFI1B-, and RUNX1-linked bleeding disorders

Mutations in the transcription factors GATA binding factor 1 (GATA1), growth factor independence 1B (GFI1B), and Runt-related transcription factor 1 (RUNX1) cause familial platelet and bleeding disorders. Mutant platelets exhibit common abnormalities including an α-granule reduction resulting in a g...

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Veröffentlicht in:	Blood 2021-07, Vol.138 (1), p.86-90
Hauptverfasser:	Van Bergen, M.G.J.M., Marneth, A.E., Hoogendijk, A.J., Van Alphen, F.P.J., Van den Akker, E., Laros-Van Gorkom, B.A.P., Hoeks, M., Simons, A., De Munnik, S.A., Janssen, J.J.W.M., Martens, J.H.A., Jansen, J.H., Meijer, A.B., Van der Reijden, B.A.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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