Lineage barcoding in mice with homing CRISPR

Classic approaches to mapping the developmental history of cells in vivo have relied on techniques that require complex interventions and often capture only a single trajectory or moment in time. We have previously described a developmental barcoding system to address these issues using syntheticall...

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Veröffentlicht in:Nature protocols 2021-04, Vol.16 (4), p.2088-2108
Hauptverfasser: Leeper, Kathleen, Kalhor, Kian, Vernet, Andyna, Graveline, Amanda, Church, George M., Mali, Prashant, Kalhor, Reza
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Sprache:eng
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