Intrapatient transfer of an uncommon carbapenemase in Nebraska
Phenotypic determination of carbapenemase production for CRE was performed using the modified carbapenem inactivation method (mCIM) as described by the Clinical and Laboratory Standards Institute (CLSI).7 According to the Nebraska Department of Health and Human Services protocol, carbapenem-resistan...
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| Veröffentlicht in: | Infection control and hospital epidemiology 2022-04, Vol.43 (4), p.535-536 |
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| container_title | Infection control and hospital epidemiology |
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| creator | Maclean, Alyssa K. W. Morrow, Stacey Abbas, Anum Vivekanandan, Renuga Cavalieri, Stephen Hanson, Nancy D. |
| description | Phenotypic determination of carbapenemase production for CRE was performed using the modified carbapenem inactivation method (mCIM) as described by the Clinical and Laboratory Standards Institute (CLSI).7 According to the Nebraska Department of Health and Human Services protocol, carbapenem-resistant isolates were sent to the Nebraska Public Health Laboratory for genotypic determination of carbapenemase production using Xpert Carba-R (Cepheid, Sunnyvale, CA). Laboratory tests revealed a normal white blood cell count of 11.8 103/mm3; elevated creatinine at 2.61 mg/dL (baseline 2.0 mg/dL); C-reactive protein (CRP) of 137 mg/L; erythrocyte sedimentation rate (ESR) > 120 mm/hour. Centers for Disease Control and Prevention website. https://www.cdc.gov/hai/organisms/cre/cre-facilities.html. |
| doi_str_mv | 10.1017/ice.2021.33 |
| format | Article |
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W. ; Morrow, Stacey ; Abbas, Anum ; Vivekanandan, Renuga ; Cavalieri, Stephen ; Hanson, Nancy D.</creator><creatorcontrib>Maclean, Alyssa K. W. ; Morrow, Stacey ; Abbas, Anum ; Vivekanandan, Renuga ; Cavalieri, Stephen ; Hanson, Nancy D.</creatorcontrib><description>Phenotypic determination of carbapenemase production for CRE was performed using the modified carbapenem inactivation method (mCIM) as described by the Clinical and Laboratory Standards Institute (CLSI).7 According to the Nebraska Department of Health and Human Services protocol, carbapenem-resistant isolates were sent to the Nebraska Public Health Laboratory for genotypic determination of carbapenemase production using Xpert Carba-R (Cepheid, Sunnyvale, CA). Laboratory tests revealed a normal white blood cell count of 11.8 103/mm3; elevated creatinine at 2.61 mg/dL (baseline 2.0 mg/dL); C-reactive protein (CRP) of 137 mg/L; erythrocyte sedimentation rate (ESR) > 120 mm/hour. 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Laboratory tests revealed a normal white blood cell count of 11.8 103/mm3; elevated creatinine at 2.61 mg/dL (baseline 2.0 mg/dL); C-reactive protein (CRP) of 137 mg/L; erythrocyte sedimentation rate (ESR) > 120 mm/hour. 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| source | ProQuest Central Essentials; MEDLINE; ProQuest Central (Alumni Edition); ProQuest Central UK/Ireland; ProQuest Central; Cambridge University Press Journals Complete |
| subjects | Bacterial Proteins beta-Lactamases Coronaviruses COVID-19 CRE bacteria Debridement Diabetes Emergency medical care Foot diseases Genes Humans Inactivation Infectious diseases International travel Laboratories Laboratory tests Leg ulcers Letter to the Editor Nebraska Patient assessment Plasmids Public health Severe acute respiratory syndrome coronavirus 2 |
| title | Intrapatient transfer of an uncommon carbapenemase in Nebraska |
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