Application of Dual Promoter Expression System for the Enhanced Heparosan Production in Bacillus megaterium

Heparosan, a capsular polysaccharide synthesized by certain pathogenic bacteria, is a promising precursor for heparin production. Heparosan production is catalyzed by the formation of KfiC-KfiA complex and the subsequent action of KfiC and KfiA proteins. Polycistronic expression of kfiC and kfiA in...

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Veröffentlicht in:	Applied biochemistry and biotechnology 2021-08, Vol.193 (8), p.2389-2402
Hauptverfasser:	Nehru, Ganesh, Tadi, Subbi Rami Reddy, Sivaprakasam, Senthilkumar
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacillus megaterium Biochemistry Biotechnology Capsular polysaccharides Chemistry Chemistry and Materials Science Controlled conditions E coli Fermentation Heparin Logit models NMR Nuclear magnetic resonance Original Article Polysaccharides Proteins
Online-Zugang:	Volltext
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