Association between instrumental activities of daily living with the change in left ventricular function in older patients with cardiovascular disease

Left ventricular dysfunction is a pathophysiologic characteristic of heart failure. Impaired instrumental activities of daily living are associated with an elevated risk of mortality and heart failure in older adults. Nevertheless, the relationship between these activities and left ventricular funct...

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Veröffentlicht in:Heart and vessels 2021-09, Vol.36 (9), p.1298-1305
Hauptverfasser: Kariya, Hidenori, Yamaoka-Tojo, Minako, Obara, Shinichi, Noda, Chiharu, Matsunaga, Atsuhiko, Ako, Junya
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container_end_page 1305
container_issue 9
container_start_page 1298
container_title Heart and vessels
container_volume 36
creator Kariya, Hidenori
Yamaoka-Tojo, Minako
Obara, Shinichi
Noda, Chiharu
Matsunaga, Atsuhiko
Ako, Junya
description Left ventricular dysfunction is a pathophysiologic characteristic of heart failure. Impaired instrumental activities of daily living are associated with an elevated risk of mortality and heart failure in older adults. Nevertheless, the relationship between these activities and left ventricular function changes remains unclear. We determined whether instrumental activities of daily living are associated with subsequent left ventricular function changes in older cardiovascular disease patients. This retrospective cohort study included 383 outpatients with cardiovascular disease (74.5 ± 5.3 years, 273 males). Patients were divided according to the Frenchay activities index tertile and followed for six months after cardiovascular disease diagnosis. The left ventricular ejection fraction and annular early diastolic velocity ( e ′) were measured for left ventricular systolic and diastolic function, respectively, at baseline and after one year. After adjusting for confounders, changes in the left ventricular ejection fraction were not significantly different. However, changes in the e ′ in the highest tertile group were significantly greater than in other groups. In the general linear model with multiple regression analysis, Frenchay activities index independently predicted the absolute change in the e ′. In older cardiovascular disease patients, higher instrumental activities of daily living were associated with preserved left ventricular relaxation.
doi_str_mv 10.1007/s00380-021-01812-3
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Impaired instrumental activities of daily living are associated with an elevated risk of mortality and heart failure in older adults. Nevertheless, the relationship between these activities and left ventricular function changes remains unclear. We determined whether instrumental activities of daily living are associated with subsequent left ventricular function changes in older cardiovascular disease patients. This retrospective cohort study included 383 outpatients with cardiovascular disease (74.5 ± 5.3 years, 273 males). Patients were divided according to the Frenchay activities index tertile and followed for six months after cardiovascular disease diagnosis. The left ventricular ejection fraction and annular early diastolic velocity ( e ′) were measured for left ventricular systolic and diastolic function, respectively, at baseline and after one year. After adjusting for confounders, changes in the left ventricular ejection fraction were not significantly different. 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subjects Activities of Daily Living
Aged
Biomedical Engineering and Bioengineering
Cardiac Surgery
Cardiology
Cardiovascular disease
Cardiovascular diseases
Cardiovascular Diseases - diagnosis
Congestive heart failure
Diastole
Ejection fraction
Female
Heart failure
Heart Failure - diagnosis
Humans
Male
Medicine
Medicine & Public Health
Multiple regression analysis
Older people
Original Article
Regression models
Retrospective Studies
Stroke Volume
Vascular Surgery
Ventricle
Ventricular Dysfunction, Left - diagnosis
Ventricular Function, Left
title Association between instrumental activities of daily living with the change in left ventricular function in older patients with cardiovascular disease
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