The clinical manifestations and risk factors in primary antiphospholipid syndrome with thrombocytopenia
To cross-sectionally analyze the clinical characteristics of primary antiphospholipid syndrome (PAPS) patients with thrombocytopenia, risk factors associated with thrombocytopenia, and risk of symptom recurrence in these patients. The inpatients with PAPS were retrospectively analyzed in Peking Unio...
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| Veröffentlicht in: | Zhōnghuá xuèyèxué zázhì 2021-01, Vol.42 (1), p.33-38 |
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| container_title | Zhōnghuá xuèyèxué zázhì |
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| creator | Li, S Lan, X L Cai, H C Zhu, T N Wang, S J Zhao, Y Q |
| description | To cross-sectionally analyze the clinical characteristics of primary antiphospholipid syndrome (PAPS) patients with thrombocytopenia, risk factors associated with thrombocytopenia, and risk of symptom recurrence in these patients.
The inpatients with PAPS were retrospectively analyzed in Peking Union Medical College Hospital from 2009 to 2019. Using the collected clinical and laboratory data, the clinical characteristics and risk of symptom recurrence in the PAPS patients with thrombocytopenia were compared with those in the PAPS patients with normal platelet counts. Univariate and multivariate logistic regression analyses were performed to screen the risk factors for thrombocytopenia.
In this study, 127 patients with PAPS were enrolled, of which 36 (28.3% ) had thrombocytopenia, with a median age of 38 years, and 63.9% were female. In the thrombocytopenia group, the average platelet count was (58.9±27.0) ×10(9)/L, and the prevalence of thrombosis and morbid pregnancy was not significantly different from that |
| doi_str_mv | 10.3760/cma.j.issn.0253-2727.2021.01.007 |
| format | Article |
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The inpatients with PAPS were retrospectively analyzed in Peking Union Medical College Hospital from 2009 to 2019. Using the collected clinical and laboratory data, the clinical characteristics and risk of symptom recurrence in the PAPS patients with thrombocytopenia were compared with those in the PAPS patients with normal platelet counts. Univariate and multivariate logistic regression analyses were performed to screen the risk factors for thrombocytopenia.
In this study, 127 patients with PAPS were enrolled, of which 36 (28.3% ) had thrombocytopenia, with a median age of 38 years, and 63.9% were female. In the thrombocytopenia group, the average platelet count was (58.9±27.0) ×10(9)/L, and the prevalence of thrombosis and morbid pregnancy was not significantly different from that</description><identifier>ISSN: 0253-2727</identifier><identifier>DOI: 10.3760/cma.j.issn.0253-2727.2021.01.007</identifier><identifier>PMID: 33677866</identifier><language>chi</language><publisher>China</publisher><subject>Adult ; Antibodies, Antiphospholipid ; Antiphospholipid Syndrome - complications ; Female ; Humans ; Male ; Retrospective Studies ; Risk Factors ; Thrombocytopenia - epidemiology</subject><ispartof>Zhōnghuá xuèyèxué zázhì, 2021-01, Vol.42 (1), p.33-38</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33677866$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Li, S</creatorcontrib><creatorcontrib>Lan, X L</creatorcontrib><creatorcontrib>Cai, H C</creatorcontrib><creatorcontrib>Zhu, T N</creatorcontrib><creatorcontrib>Wang, S J</creatorcontrib><creatorcontrib>Zhao, Y Q</creatorcontrib><title>The clinical manifestations and risk factors in primary antiphospholipid syndrome with thrombocytopenia</title><title>Zhōnghuá xuèyèxué zázhì</title><addtitle>Zhonghua Xue Ye Xue Za Zhi</addtitle><description>To cross-sectionally analyze the clinical characteristics of primary antiphospholipid syndrome (PAPS) patients with thrombocytopenia, risk factors associated with thrombocytopenia, and risk of symptom recurrence in these patients.
The inpatients with PAPS were retrospectively analyzed in Peking Union Medical College Hospital from 2009 to 2019. Using the collected clinical and laboratory data, the clinical characteristics and risk of symptom recurrence in the PAPS patients with thrombocytopenia were compared with those in the PAPS patients with normal platelet counts. Univariate and multivariate logistic regression analyses were performed to screen the risk factors for thrombocytopenia.
In this study, 127 patients with PAPS were enrolled, of which 36 (28.3% ) had thrombocytopenia, with a median age of 38 years, and 63.9% were female. In the thrombocytopenia group, the average platelet count was (58.9±27.0) ×10(9)/L, and the prevalence of thrombosis and morbid pregnancy was not significantly different from that</description><subject>Adult</subject><subject>Antibodies, Antiphospholipid</subject><subject>Antiphospholipid Syndrome - complications</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Thrombocytopenia - epidemiology</subject><issn>0253-2727</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9UMtqwzAQ1KGlCWl-oeiYi109Ysk6ltBHINBLejZ6ud7WllxLoeTva2ha2NkZdoeFWYQ2lJRcCnJvB11-lJBSKAmreMEkkyUjjJZkLiKv0PJ_vkDrlMCQinJRc05u0IJzIWUtxBK9HzuPbQ8BrO7xoAO0PmWdIYaEdXB4gvSJW21znBKGgMcJBj2d512GsYtpRg8jOJzOwU1x8PgbcodzN2sT7TnH0QfQt-i61X3y6wuv0NvT43H3Uhxen_e7h0MxUiZy4RilrdOm9UwqUXlWm61ximvj27lZIZzRTmlmhG21pKSS21rwiitbEUclX6HN791xil-nOUozQLK-73Xw8ZQatlW1UlTV1Wy9u1hPZvCuuSRr_p7DfwA0iG2l</recordid><startdate>20210114</startdate><enddate>20210114</enddate><creator>Li, S</creator><creator>Lan, X L</creator><creator>Cai, H C</creator><creator>Zhu, T N</creator><creator>Wang, S J</creator><creator>Zhao, Y Q</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20210114</creationdate><title>The clinical manifestations and risk factors in primary antiphospholipid syndrome with thrombocytopenia</title><author>Li, S ; Lan, X L ; Cai, H C ; Zhu, T N ; Wang, S J ; Zhao, Y Q</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p126t-d211fdabfe27965e28b4bd93abef3abc66dbad9a2b6cfa710574863539c50d173</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>chi</language><creationdate>2021</creationdate><topic>Adult</topic><topic>Antibodies, Antiphospholipid</topic><topic>Antiphospholipid Syndrome - complications</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Thrombocytopenia - epidemiology</topic><toplevel>online_resources</toplevel><creatorcontrib>Li, S</creatorcontrib><creatorcontrib>Lan, X L</creatorcontrib><creatorcontrib>Cai, H C</creatorcontrib><creatorcontrib>Zhu, T N</creatorcontrib><creatorcontrib>Wang, S J</creatorcontrib><creatorcontrib>Zhao, Y Q</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Zhōnghuá xuèyèxué zázhì</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, S</au><au>Lan, X L</au><au>Cai, H C</au><au>Zhu, T N</au><au>Wang, S J</au><au>Zhao, Y Q</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The clinical manifestations and risk factors in primary antiphospholipid syndrome with thrombocytopenia</atitle><jtitle>Zhōnghuá xuèyèxué zázhì</jtitle><addtitle>Zhonghua Xue Ye Xue Za Zhi</addtitle><date>2021-01-14</date><risdate>2021</risdate><volume>42</volume><issue>1</issue><spage>33</spage><epage>38</epage><pages>33-38</pages><issn>0253-2727</issn><abstract>To cross-sectionally analyze the clinical characteristics of primary antiphospholipid syndrome (PAPS) patients with thrombocytopenia, risk factors associated with thrombocytopenia, and risk of symptom recurrence in these patients.
The inpatients with PAPS were retrospectively analyzed in Peking Union Medical College Hospital from 2009 to 2019. Using the collected clinical and laboratory data, the clinical characteristics and risk of symptom recurrence in the PAPS patients with thrombocytopenia were compared with those in the PAPS patients with normal platelet counts. Univariate and multivariate logistic regression analyses were performed to screen the risk factors for thrombocytopenia.
In this study, 127 patients with PAPS were enrolled, of which 36 (28.3% ) had thrombocytopenia, with a median age of 38 years, and 63.9% were female. In the thrombocytopenia group, the average platelet count was (58.9±27.0) ×10(9)/L, and the prevalence of thrombosis and morbid pregnancy was not significantly different from that</abstract><cop>China</cop><pmid>33677866</pmid><doi>10.3760/cma.j.issn.0253-2727.2021.01.007</doi><tpages>6</tpages></addata></record> |
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| language | chi |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Adult Antibodies, Antiphospholipid Antiphospholipid Syndrome - complications Female Humans Male Retrospective Studies Risk Factors Thrombocytopenia - epidemiology |
| title | The clinical manifestations and risk factors in primary antiphospholipid syndrome with thrombocytopenia |
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